Protein detail

TMED8

Protein TMED8

Entry name
TMED8
UniProt ID
EVMP score
0.38
Frequency
3
Transmembrane count
Protein classification
Predicted intracellular proteins
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Protein TMED8
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Entrez Gene Symbol
Gene Synonym
FAM15B
Gene Description
Transmembrane p24 trafficking protein family member 8
Chromosome
14
Position
77335029-77377094
Frequency
3
EVMP Score
0.38
Fluorescence & Localization
TMED8 fluorescence
Cell Specificmonocytes
Function & Pathway
Protein Function
Predicted intracellular proteins
Molecular Function
Mediation Categories
Other mediation
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

2 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPINoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo

Regulatory Interaction Network

0 records.

Protein Complex Composition

1 record.

Component NameComponent Gene SymbolsComponent UniProt IDStoichiometryDatabaseDatabase IDsReferences
HT_DM_Cluster328ACBD3BLZF1TMED8Q6PL24Q9H2G9Q9H3P71:1:1CompleatCompleat:HC320822036573

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyMass spectrometryWestern blotting6328481363468472736263165370405073913660339229506
Sequence, Structure & Domains

Sequences

Length
325
Mass
35,740
Sequence
MSDLQAAEGPGSWSPTARPGSAGGVGDCQGVEGSQAAASENEDLENKDTSLLASATDPEPCSSPHRPQMVSPVSKDATEDLRKATGPLEAQALVKQDLLPADQAQVLNEMAKYQVPQRSGDIVMIQSEHTGAIDVLSADLESADLLGDHRKVSPPLMAPPCIWTFAKVKEFKSKLGKEKNSRLVVKRGEVVTIRVPTHPEGKRVCWEFATDDYDIGFGVYFDWTPVTSTDITVQVSDSSDDEDEEEEEEEEIEEPVPAGDVERGSRSSLRGRYGEVMPVYRRDSHRDVQAGSHDYPGEGIYLLKFDNSYSLLRNKTLYFHIYYTS

3D Structural Models

Domain & Motif Annotations

Compositional Bias
238..254; Acidic residues
Domain (FT)
159..323; GOLD
Region
1..78; Disordered; 232..267; Disordered
Clinical Relevance
Antibody
Interaction Protein
ENSG00000106803
Interaction Count
1
Interaction Dataset
biogrid_opencell