Protein detail
OLFM4
Olfactomedin-4 (OLM4) (Antiapoptotic protein GW112) (G-CSF-stimulated clone 1 protein) (hGC-1) (hOLfD)
Entry name OLFM4 | UniProt ID | EVMP confidence score 0.50 |
Supporting publications (n) 7 | Transmembrane count | Protein classification Predicted secreted proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Olfactomedin-4 (OLM4) (Antiapoptotic protein GW112) (G-CSF-stimulated clone 1 protein) (hGC-1) (hOLfD)
Protein Class
Predicted secreted proteins
Protein Function
Predicted secreted proteins
Ensembl
Entrez Gene Symbol
Gene Synonym (3)
GC1GW112OlfD
Gene Description
Olfactomedin 4
Chromosome
13
Position
53028813-53052057
Supporting publications (n)
7
EVMP confidence score
0.50
Fluorescence & Localization
Cell SpecificEsophageal apical cells
Function & Pathway
Protein Function
Predicted secreted proteins
Cellular Component (13)
- GO:0005576 extracellular region
- GO:0005615 extracellular space
- GO:0005654 nucleoplasm
- GO:0005739 mitochondrion
- GO:0005829 cytosol
- GO:0005886 plasma membrane
- GO:0032991 protein-containing complex
- GO:0035580 specific granule lumen
- GO:0042581 specific granule
- GO:0045171 intercellular bridge
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Molecular Function (3)
Biological Process (3)
Mediation Categories (2)
Adhesion and uptake mediationImmune mediation
Relations & Evidence16
Ligand-Receptor Signaling (14)
14 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| secreted | secreted | UniProt_keyword | Yes | ||||
| secreted | secreted | UniProt_location | Yes | ||||
| secreted | secreted | HPA_secretome | Yes | ||||
| secreted | secreted | OmniPath | Yes |
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Protein Complex Composition (1)
Sequence, Structure & Domains
Sequences
Length
510
Mass
57,280
Sequence
MRPGLSFLLALLFFLGQAAGDLGDVGPPIPSPGFSSFPGVDSSSSFSSSSRSGSSSSRSLGSGGSVSQLFSNFTGSVDDRGTCQCSVSLPDTTFPVDRVERLEFTAHVLSQKFEKELSKVREYVQLISVYEKKLLNLTVRIDIMEKDTISYTELDFELIKVEVKEMEKLVIQLKESFGGSSEIVDQLEVEIRNMTLLVEKLETLDKNNVLAIRREIVALKTKLKECEASKDQNTPVVHPPPTPGSCGHGGVVNISKPSVVQLNWRGFSYLYGAWGRDYSPQHPNKGLYWVAPLNTDGRLLEYYRLYNTLDDLLLYINARELRITYGQGSGTAVYNNNMYVNMYNTGNIARVNLTTNTIAVTQTLPNAAYNNRFSYANVAWQDIDFAVDENGLWVIYSTEASTGNMVISKLNDTTLQVLNTWYTKQYKPSASNAFMVCGVLYATRTMNTRTEEIFYYYDTNTGKEGKLDIVMHKMQEKVQSINYNPFDQKLYVYNDGYLLNYDLSVLQKPQ
Domain & Motif Annotations
Coiled Coil
155..234
Domain (CC)
The olfactomedin-like domain is involved in the interaction with cadherin.
Domain (FT)
245..507; Olfactomedin-like
Clinical Relevance
Antibody
Supporting Publications7
| PMID | Title | Related sentences |
|---|---|---|
| 30353492 | Extracellular Vesicles Released by Glioblastoma Cells Stimulate Normal Astrocytes to Acquire a Tumor-Supportive Phenotype Via p53 and MYC Signaling Pathways. | No related sentences available |
| 30760538 | Microvesicle Proteomic Profiling of Uterine Liquid Biopsy for Ovarian Cancer Early Detection. | No related sentences available |
| 31320591 | Exosomes regulate neurogenesis and circuit assembly. | No related sentences available |
| 37686366 | Identification of a Non-Invasive Urinary Exosomal Biomarker for Diabetic Nephropathy Using Data-Independent Acquisition Proteomics. | No related sentences available |
| 39532703 | Proteomic Insights Into Gingival Crevicular Extracellular Vesicles in Periodontitis and Gestational Diabetes: An Exploratory Study. | No related sentences available |
| 40091455 | Potential Role of Menstrual Fluid-Derived Small Extracellular Vesicle Proteins in Endometriosis Pathogenesiss. | No related sentences available |
| 41201090 | Identification of molecular markers and exploration of the oncogenic role of exomeres in hepatocellular carcinoma. | No related sentences available |