Protein detail

CF299

Cilia- and flagella-associated protein 299

Protein symbol CF299	UniProt ID Q6V702	EVMP score 0.38
Frequency 1	Transmembrane count	Protein classification Predicted intracellular proteins

EVMP score: annotation confidence score.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40

Basic Information

Protein Names

Cilia- and flagella-associated protein 299

Protein Class

Predicted intracellular proteins

Protein Function

Predicted intracellular proteins

Ensembl

ENSG00000197826

Entrez Gene Symbol

CFAP299

Gene Synonym

C4orf22

Gene Description

Cilia and flagella associated protein 299

Chromosome

Position

80335730-80963750

Frequency

EVMP Score

0.38

Fluorescence & Localization

Tissue SpecificbrainCell SpecificAstrocytes

Function & Pathway

Protein Function

Predicted intracellular proteins

Cellular Component

Molecular Function

GO:0005515 protein binding

Biological Process

Mediation Categories

Other mediation

Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

4 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
intracellular	intracellular	ComPPI	No	No	No	No	No
intracellular	intracellular	GO_Intercell	No	No	No	No	No
intracellular	intracellular	UniProt_location	No	No	No	No	No
intracellular	intracellular	OmniPath	No	No	No	No	No

Regulatory Interaction Network

0 records.

Protein Complex Composition

1 record.

Component Name	Component Gene Symbols	Component UniProt ID	Stoichiometry	Database	Database IDs	References
	CFAP299	Q6V702	2	PDB	PDB:9fgp

Isolation & Detection Technology

1 record.

EV Isolation Method	Detection Method	Number of References	References
Differential Ultracentrifugation	Mass spectrometry	1	39363010

Sequence, Structure & Domains

Sequences

Length

233

Mass

26,869

Sequence

MDQEEGLKALDNIVTQFNAYEDFLDSQITTVDLYYLEDETLARQLVELGYRGTGERVKREDFEARKAAIEIARLAERAQQKTLTSAGKDLQDNFLTALAMREEDNRSGKLSSVIFIRDRNSHGQEISGYIDYAHRLKTEDFEVYFTGKKRLLPRPTDISFYNWDADIAVSNSSPNYQVIADNPEGLLFRYKRDRKILNVDPKAQPGDNSTRITILTELYVQAVIFDHISRRKT

Alternative Products

Event=Alternative splicing; Named isoforms=3; Name=2; IsoId=Q6V702-2; Sequence=Displayed; Name=1; IsoId=Q6V702-1; Sequence=VSP_037233; Name=3; IsoId=Q6V702-3; Sequence=VSP_037234, VSP_037235

Alternative Sequence

111; S -> SLNQQETDAAHILKKQLA (in isoform 1); 112..156; SVIFIRDRNSHGQEISGYIDYAHRLKTEDFEVYFTGKKRLLPRPT -> AGVQWHHLGSLQPLPPGFKEFSCFSLPSGWDYRHAPPHPVRDLYS (in isoform 3); 157..233; Missing (in isoform 3)

3D Structural Models

3D Structure

Electron microscopy (1); X-ray crystallography (1)

Domain & Motif Annotations

Clinical Relevance

Antibody

HPA043383

Interaction Protein

ENSG00000116044

Interaction Count

Interaction Dataset

intact_biogrid