Protein detail
LRC69
Leucine-rich repeat-containing protein 69
Entry name LRC69 | UniProt ID | EVMP confidence score 0.38 |
Supporting publications (n) 1 | Transmembrane count | Protein classification Predicted intracellular proteins |
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40Basic Information10
Protein Names
Leucine-rich repeat-containing protein 69
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Description
Leucine rich repeat containing 69
Chromosome
8
Position
91101832-91219257
Supporting publications (n)
1
EVMP confidence score
0.38
Fluorescence & Localization2
Cell SpecificBreast lactating cellsSingle-Nuclei Brain Specificlower rhombic lip
Function & Pathway3
Protein Function
Predicted intracellular proteins
Biological Process (3)
Mediation Categories
Other mediation
Relations & Evidence3
Ligand-Receptor Signaling (2)
2 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion ChromatographyImmunoaffinity Capture | Mass spectrometry | 14 | 4098587926826536385901323811336840465195373224753649718434064677344735053091508432560723361468343820710632854315 |
Sequence, Structure & Domains8
Sequences
Length
347
Mass
39,592
Sequence
MTERLLIKALSGGKNTKIITLNGKKMTKMPSALGKLPGLKTLVLQNNLIPKVCPELCNLTQLTTLNLGNNLLEEVPEEMKYLTSLKNLHLSGNRICRFAPGACDGLQNLILLNLNNNHLTQLPQEVSRLKSLTYMSINYNQLASIPRELCFLENLVELQLNYNQLICIPEEIKFLKKLQKLLLARNNIGVLPEELCDLKKLRILDIAGNIIQIFPSGFQDLKLREFYCEGNPLFLQQPVISTQQENVWSLQEITSRFVMNQLAENNPFLMDDIERYPQVRSMISQGKTCAICGQYFITVWLECVRFVPPPKDWKISKNLKLVPLQVLICSYKCFTQRDPNLFGIAQV
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q6ZNQ3-1; Sequence=Displayed; Name=2; IsoId=Q6ZNQ3-2; Sequence=VSP_033810
Alternative Sequence
62..217; Missing (in isoform 2)
Domain & Motif Annotations
Repeat
38..60; LRR 1; 61..82; LRR 2; 84..105; LRR 3; 108..129; LRR 4; 131..153; LRR 5; 154..175; LRR 6; 177..199; LRR 7; 200..222; LRR 8
Protein Families
LRRC69 family
Sequence Similarities
Belongs to the LRRC69 family.
Clinical Relevance1
Antibody
Supporting Publications1
| PMID | Title | Abstract |
|---|---|---|
| 40326690 | Rapid Identification of Esophageal Squamous Cell Carcinoma Biomarkers by MALDI-TOF MS Fingerprinting of Extracellular Vesicles. | No abstract available |