Protein detail

GADL1

Acidic amino acid decarboxylase GADL1 (Aspartate 1-decarboxylase) (ADC) (HuADC) (EC 4.1.1.11) (Cysteine sulfinic acid decarboxylase) (CSADC) (HuCSADC) (EC 4.1.1.29) (Glutamate decarboxylase-like protein 1)

Protein symbol
GADL1
UniProt ID
EVMP score
0.38
Frequency
1
Transmembrane count
Protein classification
EnzymesPredicted intracellular proteins
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Acidic amino acid decarboxylase GADL1 (Aspartate 1-decarboxylase) (ADC) (HuADC) (EC 4.1.1.11) (Cysteine sulfinic acid decarboxylase) (CSADC) (HuCSADC) (EC 4.1.1.29) (Glutamate decarboxylase-like protein 1)
Protein Class
EnzymesPredicted intracellular proteins
Protein Function
  • Enzymes
  • Predicted intracellular proteins
  • ENZYME proteins:Lyases
Entrez Gene Symbol
Gene Description
Glutamate decarboxylase like 1
Chromosome
3
Position
30726197-30894661
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Cell SpecificAstrocytes
Function & Pathway
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

2 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularGO_IntercellNoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo

Regulatory Interaction Network

0 records.

Protein Complex Composition

2 records.

Component NameComponent Gene SymbolsComponent UniProt IDStoichiometryDatabaseDatabase IDsReferences
ARL13BGADL1Q3SXY8Q6ZQY30:0hu.MAP2
ANKRD50ARL13BGADL1Q3SXY8Q6ZQY3Q9ULJ70:0:0hu.MAP

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationR Sequencing139363010
Sequence, Structure & Domains

Sequences

Length
521
Mass
59,246
Sequence
MSSDSDRQCPVDGDIDQQEMIPSKKNAVLVDGVVLNGPTTDAKAGEKFVEEACRLIMEEVVLKATDVNEKVCEWRPPEQLKQLLDLEMRDSGEPPHKLLELCRDVIHYSVKTNHPRFFNQLYAGLDYYSLVARFMTEALNPSVYTYEVSPVFLLVEEAVLKKMIEFIGWKEGDGIFNPGGSVSNMYAMNLARYKYCPDIKEKGLSGSPRLILFTSAECHYSMKKAASFLGIGTENVCFVETDGRGKMIPEELEKQVWQARKEGAAPFLVCATSGTTVLGAFDPLDEIADICERHSLWLHVDASWGGSALMSRKHRKLLHGIHRADSVAWNPHKMLMAGIQCCALLVKDKSDLLKKCYSAKASYLFQQDKFYDVSYDTGDKSIQCSRRPDAFKFWMTWKALGTLGLEERVNRALALSRYLVDEIKKREGFKLLMEPEYANICFWYIPPSLREMEEGPEFWAKLNLVAPAIKERMMKKGSLMLGYQPHRGKVNFFRQVVISPQVSREDMDFLLDEIDLLGKDM
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q6ZQY3-1; Sequence=Displayed; Name=2; IsoId=Q6ZQY3-3; Sequence=VSP_036227
Alternative Sequence
419..521; Missing (in isoform 2)

3D Structural Models

Domain & Motif Annotations

Protein Families
Group II decarboxylase family
Sequence Similarities
Belongs to the group II decarboxylase family.
Clinical Relevance