Protein detail
R9BP
Regulator of G-protein signaling 9-binding protein (RGS9-anchoring protein)
Entry name R9BP | UniProt ID | EVMP confidence score 0.40 |
Supporting publications (n) 1 | Transmembrane count 1 | Protein classification Disease related genesHuman disease related genesPredicted membrane proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Regulator of G-protein signaling 9-binding protein (RGS9-anchoring protein)
Protein Class (3)
Disease related genesHuman disease related genesPredicted membrane proteins
Protein Function (2)
- Disease related genes
- Human disease related genes:Nervous system diseases:Eye disease
Transmembrane
211..231; Helical; Anchor for type IV membrane protein
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym (3)
FLJ45744PERRSR9AP
Gene Description
Regulator of G protein signaling 9 binding protein
Chromosome
19
Position
32675848-32678300
Supporting publications (n)
1
EVMP confidence score
0.40
Function & Pathway
Protein Function (2)
- Disease related genes
- Human disease related genes:Nervous system diseases:Eye disease
Cellular Component (3)
Biological Process (3)
Reactome (3)
Canonical Pathways (3)
- M5880 Naba ecm affiliated
- M5885 Naba matrisome associated
- M5889 Naba matrisome
Mediation Categories
Other mediation
Relations & Evidence15
Ligand-Receptor Signaling (14)
14 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| gpcr | receptor | DGIdb | Yes | ||||
| receptor | receptor | OmniPath | Yes | ||||
| intracellular | intracellular | ComPPI | |||||
| intracellular | intracellular | OmniPath | |||||
| transmembrane | transmembrane | UniProt_location | |||||
| transmembrane | transmembrane | UniProt_topology | |||||
| transmembrane | transmembrane | UniProt_keyword | |||||
| transmembrane_predicted | transmembrane | OmniPath | |||||
| transmembrane | transmembrane | Ramilowski_location | |||||
| transmembrane | transmembrane | OmniPath |
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Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationSize Exclusion Chromatography | Western Blotting | 1 | 36741391 |
Sequence, Structure & Domains
Sequences
Length
235
Mass
25,148
Sequence
MAREECKALLDGLNKTTACYHHLVLTVGGSADSQNLRQELQKTRQKAQELAVSTCARLTAVLRDRGLAADERAEFERLWVAFSGCLDLLEADMRRALELGAAFPLHAPRRPLVRTGVAGASSGVAARALSTRSLRLEAEGDFDVADLRELEREVLQVGEMIDNMEMKVNVPRWTVQARQAAGAELLSTVSAGPSSVVSLQERGGGCDPRKALAAILFGAVLLAAVALAVCVAKLS
Domain & Motif Annotations
Coiled Coil
29..54; 144..169
Region
153..200; SNARE-like
Protein Families
RGS7BP/RGS9BP family
Sequence Similarities
Belongs to the RGS7BP/RGS9BP family.
Clinical Relevance
Antibody
Supporting Publications1
| PMID | Title | Related sentences |
|---|---|---|
| 40089067 | Metabolic Reprogramming Into a Glycolysis Phenotype Induced by Extracellular Vesicles Derived From Prostate Cancer Cells. | No related sentences available |