Protein detail
FA47E
Protein FAM47E
Entry name FA47E | UniProt ID | EVMP confidence score 0.53 |
Supporting publications (n) 1 | Transmembrane count | Protein classification Predicted intracellular proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Protein FAM47E
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym (2)
FLJ42946LOC100129583
Gene Description
Family with sequence similarity 47 member E
Chromosome
4
Position
76214040-76283783
Supporting publications (n)
1
EVMP confidence score
0.53
Fluorescence & Localization
Tissue Specificskin 1Cell SpecificEndometrial glandular cells
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component (3)
Molecular Function (2)
Biological Process (3)
Mediation Categories
Other mediation
Relations & Evidence4
Ligand-Receptor Signaling (3)
3 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | GO_Intercell | |||||
| intracellular | intracellular | UniProt_location | |||||
| intracellular | intracellular | OmniPath |
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion ChromatographyImmunoaffinity Capture | Mass spectrometryMass spectrometry [LTQ-FT Ultra]Mass spectrometry [QTOF] | 37 | 40985879286801522682653640189497277926493792675636064647260987143811336840465195373224753330447836497184340646773889596233592500328543153447350538891077389179263256072331617158329169864130796836146834333098264084070131805958386070623223097038207106345762463720451539001700374386383920704741068253 |
Sequence, Structure & Domains
Sequences
Length
393
Mass
45,662
Sequence
MADRRRRLRPGTLAPVREGVNCRSRCFTKHKNGLKFPTSLHSRQLVFPRKGLDDFRKGCPPCTGLVTQVPVEGFLPQIYHRAPQLAPKKRQIKLLKEADVLSKLSPAQQARKAFLEDVEAHLTPHPLALYLNLEEAMPIELLSKVLEVLDPDRKLEDTWAYCQDTRKGMKEPTKLLKKHSTQVYLGPSKKTSVSNAGQWLYEEKPHKMDLLHENGPRPGLHENGISDIDEEFILKQFDIDYETKPSHDALHTMKLNQVPLELKRSVGLSKLQETEFFQKLGYERKLQKPQNPYKPKWVKMRYGAWYLNPKLWKKQRVDEPLVDPEVSHKAQEENFKKELQEQEELLADLHGTVAFKDFILSRGYRTPRFLENMYIGKECKRACNKTPIKRTQA
Alternative Products
Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q6ZV65-3; Sequence=Displayed; Name=2; IsoId=Q6ZV65-2; Sequence=VSP_040931, VSP_040932, VSP_040933; Name=3; IsoId=Q6ZV65-1; Sequence=VSP_040934
Alternative Sequence
1..113; Missing (in isoform 2); 114..140; FLEDVEAHLTPHPLALYLNLEEAMPIE -> MQMSVPCVLSSLQNHEPNKPLFTTQSQ (in isoform 2); 223; N -> NVCKAVSDFCKWVTTF (in isoform 2); 343..393; EELLADLHGTVAFKDFILSRGYRTPRFLENMYIGKECKRACNKTPIKRTQA -> SIFKKAMDI (in isoform 3)
Domain & Motif Annotations
Coiled Coil
326..354
Protein Families
FAM47 family
Sequence Similarities
Belongs to the FAM47 family.
Clinical Relevance
Antibody
Supporting Publications1
| PMID | Title | Related sentences |
|---|---|---|
| 38731868 | The Deep Proteomics Approach Identified Extracellular Vesicular Proteins Correlated to Extracellular Matrix in Type One and Two Endometrial Cancer. | No related sentences available |