Protein detail
GRIN1
G protein-regulated inducer of neurite outgrowth 1 (GRIN1)
Protein symbol GRIN1 | UniProt ID | EVMP score 0.63 |
Frequency 8 | Transmembrane count | Protein classification Predicted intracellular proteins |
Basic Information
Protein Names
G protein-regulated inducer of neurite outgrowth 1 (GRIN1)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
GRIN1KIAA1893
Gene Description
G protein regulated inducer of neurite outgrowth 1
Chromosome
5
Position
176595802-176610156
Frequency
8
EVMP Score
0.63
Fluorescence & Localization
Tissue SpecifictestisCell SpecificEarly spermatids
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Reactome
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
| plasma_membrane | plasma_membrane | UniProt_location | No | No | No | No | No |
| plasma_membrane | plasma_membrane | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
1 record.
| Source Protein Symbol | Source UniProt ID | Target Protein Symbol | Target UniProt ID | Is Directed | Is Stimulation | Is Inhibition | Database | References |
|---|---|---|---|---|---|---|---|---|
| MECP2 | P51608 | GRIN1 | Q7Z2K8 | Yes | Yes | No | SIGNOR | SIGNOR:18511691 |
Protein Complex Composition
0 records.
Sequence, Structure & Domains
Sequences
Length
1,008
Mass
102,399
Sequence
MDTAEDPAWLQLLQKDSSPPGPRPTAFFCPQDGSLGAGSSAMRDYCPSQQKASPAPPRHTPDQSPGMESRHRSPSGAGEGASCSDGPRGSLACPSPTCFSPQESPSKETLEAHGASISGTPEATTSGKPEPVSSVKTEPKSSDDRNPMFLEKMDFKSSKQADSTSIGKEDPGSSRKADPMFTGKAEPEILGKGDPVAPGRMDPMTVRKEDLGSLGKVDPLCSSKTYTVSPRKEDPGSLRKVDPVSSDKVDPVFPRKEEPRYSGKEHPVSSEKVAPTSAEKVDLVLSGKRDPGPSGKADPMPLESMDSASTGKTEPGLLGKLIPGSSGKNGPVSSGTGAPGSLGRLDPTCLGMADPASVGNVETVPATKEDSRFLGKMDPASSGEGRPVSGHTDTTASAKTDLTSLKNVDPMSSGKVDPVSLGKMDPMCSGKPELLSPGQAERVSVGKAGTVSPGKEDPVSSRREDPISAGSRKTSSEKVNPESSGKTNPVSSGPGDPRSLGTAGPPSAVKAEPATGGKGDPLSSEKAGLVASGKAAPTASGKAEPLAVGKEDPVSKGKADAGPSGQGDSVSIGKVVSTPGKTVPVPSGKVDPVSLGKAEAIPEGKVGSLPLEKGSPVTTTKADPRASGKAQPQSGGKAETKLPGQEGAAAPGEAGAVCLKKETPQASEKVDPGSCRKAEPLASGKGEPVSLGKADSAPSRKTESPSLGKVVPLSLEKTKPSSSSRQLDRKALGSARSPEGARGSEGRVEPKAEPVSSTEASSLGQKDLEAAGAERSPCPEAAAPPPGPRTRDNFTKAPSWEASAPPPPREDAGTQAGAQACVSVAVSPMSPQDGAGGSAFSFQAAPRAPSPPSRRDAGLQVSLGAAETRSVATGPMTPQAAAPPAFPEVRVRPGSALAAAVAPPEPAEPVRDVSWDEKGMTWEVYGAAMEVEVLGMAIQKHLERQIEEHGRQGAPAPPPAARAGPGRSGSVRTAPPDGAAKRPPGLFRALLQSVRRPRCCSRAGPTAE
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q7Z2K8-1; Sequence=Displayed; Name=2; IsoId=Q7Z2K8-2; Sequence=VSP_018546, VSP_018547
Alternative Sequence
748..798; VEPKAEPVSSTEASSLGQKDLEAAGAERSPCPEAAAPPPGPRTRDNFTKAP -> QASARPVPRAAAECAPAAVLLAGGTHGRVICPHFVRPSFRPSQAPFLITGP (in isoform 2); 799..1008; Missing (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Compositional Bias
117..127; Polar residues; 137..159; Basic and acidic residues; 167..178; Basic and acidic residues; 230..269; Basic and acidic residues; 279..291; Basic and acidic residues; 326..336; Polar residues; 391..406; Polar residues; 454..466; Basic and acidic residues; 481..491; Polar residues; 549..559; Basic and acidic residues; 643..656; Low complexity; 659..679; Basic and acidic residues; 742..752; Basic and acidic residues; 755..764; Polar residues; 838..847; Low complexity
Region
1..859; Disordered; 899..1008; Interaction with GNAO1; 943..986; Disordered