Protein detail
PTAR1
Protein prenyltransferase alpha subunit repeat-containing protein 1
Entry name PTAR1 | UniProt ID | EVMP confidence score 0.50 |
Supporting publications (n) 7 | Transmembrane count | Protein classification Predicted intracellular proteins |
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40Basic Information10
Protein Names
Protein prenyltransferase alpha subunit repeat-containing protein 1
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Description
Protein prenyltransferase alpha subunit repeat containing 1
Chromosome
9
Position
69709522-69760011
Supporting publications (n)
7
EVMP confidence score
0.50
Fluorescence & Localization5
Tissue Specificbone marrowCell SpecificLate spermatidsBlood Cell SpecificeosinophilBlood Lineage Specificgranulocytes
Function & Pathway6
Protein Function
Predicted intracellular proteins
Cellular Component (2)
Molecular Function (2)
Biological Process (3)
Canonical Pathways
M33 Pid glypican 1pathway
Mediation Categories
Other mediation
Relations & Evidence8
Ligand-Receptor Signaling (3)
3 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Protein Complex Composition (4)
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationSize Exclusion Chromatography | Mass spectrometry | 1 | 40689422 |
Sequence, Structure & Domains11
Sequences
Length
402
Mass
46,405
Sequence
MAETSEEVAVLVQRVVKDITNAFRRNPHIDEIGLIPCPEARYNRSPIVLVENKLGVESWCVKFLLPYVHNKLLLYRTRKQWLNRDELIDVTCTLLLLNPDFTTAWNVRKELILSGTLNPIKDLHLGKLALTKFPKSPETWIHRRWVLQQLIQETSLPSFVTKGNLGTIPTERAQRLIQEEMEVCGEAAGRYPSNYNAWSHRIWVLQHLAKLDVKILLDELSSTKHWASMHVSDHSGFHYRQFLLKSLISQTVIDSSVMEQNPLRSEPALVPPKDEEAAVSTEEPRINLPHLLEEEVEFSTDLIDSYPGHETLWCHRRHIFYLQHHLNAGSQLSQAMEVDGLNDSSKQGYSQETKRLKRTPVPDSLGLEMEHRFIDQVLSTCRNVEQARFASAYRKWLVTLSQ
3D Structural Models
Turn
150..153; 281..283; 284..286
Helix
7..25; 58..60; 61..76; 84..97; 102..113; 119..132; 137..149; 172..190; 195..207; 213..229; 234..248; 290..305; 310..323; 368..379; 384..397
Beta Strand
31..35; 42..44; 46..50; 53..57; 209..211
3D Structure
X-ray crystallography (5)
Domain & Motif Annotations
Repeat
81..115; PFTA 1; 116..152; PFTA 2; 171..210; PFTA 3; 211..250; PFTA 4; 289..325; PFTA 5; 366..400; PFTA 6
Region
263..282; Disordered
Protein Families
Protein prenyltransferase subunit alpha family
Sequence Similarities
Belongs to the protein prenyltransferase subunit alpha family.
Clinical Relevance4
Supporting Publications7
| PMID | Title | Abstract |
|---|---|---|
| 24505114 | Proteomics analysis of cancer exosomes using a novel modified aptamer-based array (SOMAscan™) platform. | These included proteins of known association with cancer exosomes such as MFG-E8, integrins, and MET, and also those less widely reported as exosomally associated, such as ROR1 and ITIH4. |
| 28963552 | Radiation alters the cargo of exosomes released from squamous head and neck cancer cells to promote migration of recipient cells. | No abstract available |
| 30608700 | Quantitative Proteomic Analysis of Small and Large Extracellular Vesicles (EVs) Reveals Enrichment of Adhesion Proteins in Small EVs. | No abstract available |
| 31588238 | Dual-platform affinity proteomics identifies links between the recurrence of ovarian carcinoma and proteins released into the tumor microenvironment. | No abstract available |
| 38731868 | The Deep Proteomics Approach Identified Extracellular Vesicular Proteins Correlated to Extracellular Matrix in Type One and Two Endometrial Cancer. | No abstract available |
| 40098346 | Toward Identification of Markers for Brain-Derived Extracellular Vesicles in Cerebrospinal Fluid: A Large-Scale, Unbiased Analysis Using Proximity Extension Assays. | No abstract available |
| 40784529 | Serum-derived exosome proteomics unveils the distinct and adjustable nature of the dampness constitution in traditional Chinese medicine. | No abstract available |