Protein detail

LRP11

Low-density lipoprotein receptor-related protein 11 (LRP-11)

Protein symbol
LRP11
UniProt ID
EVMP score
0.50
Frequency
4
Transmembrane count
1
Protein classification
Basic Information
Protein Names
Low-density lipoprotein receptor-related protein 11 (LRP-11)
Protein Function
Predicted intracellular proteins
Transmembrane
451..473; Helical
Transmembrane Count
1
Entrez Gene Symbol
Frequency
4
EVMP Score
0.50
Fluorescence & Localization
Tissue SpecifictestisCell SpecificEarly spermatids
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Mediation Categories
Other mediation
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

37 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
receptorreceptorHPMRNoYesNoYesNo
receptorreceptorSurfaceomeNoYesNoYesNo
receptorreceptorRamilowski2015NoYesNoYesNo
receptorreceptorLRdbNoYesNoYesNo
receptorreceptorBaccin2019NoYesNoYesNo
low_density_lipoproteinreceptorAlmen2009NoYesNoYesNo
low_density_lipoprotein_ldl_receptor_and_ldl_receptor_related_proteinsreceptorHPMRNoYesNoYesNo
ldlrreceptorSurfaceomeNoYesNoYesNo
receptorreceptorOmniPathNoYesNoYesNo
extracellularextracellularHPMRNoNoNoYesNo
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Regulatory Interaction Network

0 records.

Protein Complex Composition

0 records.

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyMass spectrometry|Western blottingMass spectrometryMass spectrometry [LTQ-FT Ultra]Western blotting3380145953091508437670049
Sequence, Structure & Domains

Sequences

Length
500
Mass
53,311
Sequence
MASVAQESAGSQRRLPPRHGALRGLLLLCLWLPSGRAALPPAAPLSELHAQLSGVEQLLEEFRRQLQQERPQEELELELRAGGGPQEDCPGPGSGGYSAMPDAIIRTKDSLAAGASFLRAPAAVRGWRQCVAACCSEPRCSVAVVELPRRPAPPAAVLGCYLFNCTARGRNVCKFALHSGYSSYSLSRAPDGAALATARASPRQEKDAPPLSKAGQDVVLHLPTDGVVLDGRESTDDHAIVQYEWALLQGDPSVDMKVPQSGTLKLSHLQEGTYTFQLTVTDTAGQRSSDNVSVTVLRAAYSTGGCLHTCSRYHFFCDDGCCIDITLACDGVQQCPDGSDEDFCQNLGLDRKMVTHTAASPALPRTTGPSEDAGGDSLVEKSQKATAPNKPPALSNTEKRNHSAFWGPESQIIPVMPDSSSSGKNRKEESYIFESKGDGGGGEHPAPETGAVLPLALGLAITALLLLMVACRLRLVKQKLKKARPITSEESDYLINGMYL
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q86VZ4-1; Sequence=Displayed; Name=2; IsoId=Q86VZ4-2; Sequence=VSP_017535, VSP_017536
Alternative Sequence
205..237; EKDAPPLSKAGQDVVLHLPTDGVVLDGRESTDD -> GKRATEGPALARALETRSALAKLEAKHTRAKLF (in isoform 2); 238..500; Missing (in isoform 2)

3D Structural Models

Domain & Motif Annotations

Domain (FT)
99..184; MANSC; 210..305; PKD; 309..345; LDL-receptor class A
Region
358..445; Disordered
Protein Families
LDLR family
Sequence Similarities
Belongs to the LDLR family.
Clinical Relevance