Protein detail

LRP11

Low-density lipoprotein receptor-related protein 11 (LRP-11)

Entry name
LRP11
UniProt ID
Q86VZ4
EVMP confidence score
0.28
Supporting publications (n)
4
Transmembrane count
1
Protein classification
Basic Information
Protein Names
Low-density lipoprotein receptor-related protein 11 (LRP-11)
Protein Function
Predicted intracellular proteins
Transmembrane
451..473; Helical
Transmembrane Count
1
Ensembl
ENSG00000120256
Entrez Gene Symbol
LRP11
Supporting publications (n)
4
EVMP confidence score
0.28
Fluorescence & Localization
LRP11 fluorescence
Tissue SpecifictestisCell SpecificEarly spermatids
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
GO:0005886 plasma membrane
Molecular Function
GO:0051219 phosphoprotein binding
Biological Process (3)
Mediation Categories
Other mediation
Relations & Evidence38

Ligand-Receptor Signaling (37)

37 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
plasma_membrane_transmembraneplasma_membrane_transmembraneCSPAYes
plasma_membrane_transmembraneplasma_membrane_transmembraneHPMRYes
plasma_membrane_transmembraneplasma_membrane_transmembraneOmniPathYes
cell_surfacecell_surfaceSurfaceomeYes
cell_surfacecell_surfaceconnectomeDB2020Yes
cell_surfacecell_surfaceOmniPathYes
receptorreceptortalklrYesYes
receptorreceptorconnectomeDB2020YesYes
receptorreceptoriTALKYesYes
receptorreceptorAlmen2009YesYes
Page 3 of 4PreviousNext

Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyMass spectrometry|Western blottingMass spectrometryMass spectrometry [LTQ-FT Ultra]Western blotting3380145953091508437670049
Sequence, Structure & Domains

Sequences

Length
500
Mass
53,311
Sequence
MASVAQESAGSQRRLPPRHGALRGLLLLCLWLPSGRAALPPAAPLSELHAQLSGVEQLLEEFRRQLQQERPQEELELELRAGGGPQEDCPGPGSGGYSAMPDAIIRTKDSLAAGASFLRAPAAVRGWRQCVAACCSEPRCSVAVVELPRRPAPPAAVLGCYLFNCTARGRNVCKFALHSGYSSYSLSRAPDGAALATARASPRQEKDAPPLSKAGQDVVLHLPTDGVVLDGRESTDDHAIVQYEWALLQGDPSVDMKVPQSGTLKLSHLQEGTYTFQLTVTDTAGQRSSDNVSVTVLRAAYSTGGCLHTCSRYHFFCDDGCCIDITLACDGVQQCPDGSDEDFCQNLGLDRKMVTHTAASPALPRTTGPSEDAGGDSLVEKSQKATAPNKPPALSNTEKRNHSAFWGPESQIIPVMPDSSSSGKNRKEESYIFESKGDGGGGEHPAPETGAVLPLALGLAITALLLLMVACRLRLVKQKLKKARPITSEESDYLINGMYL
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q86VZ4-1; Sequence=Displayed; Name=2; IsoId=Q86VZ4-2; Sequence=VSP_017535, VSP_017536
Alternative Sequence
205..237; EKDAPPLSKAGQDVVLHLPTDGVVLDGRESTDD -> GKRATEGPALARALETRSALAKLEAKHTRAKLF (in isoform 2); 238..500; Missing (in isoform 2)

Domain & Motif Annotations

Domain (FT)
99..184; MANSC; 210..305; PKD; 309..345; LDL-receptor class A
Region
358..445; Disordered
Protein Families
LDLR family
Sequence Similarities
Belongs to the LDLR family.
Supporting Publications4
PMIDTitleRelated sentences
27894104Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.No related sentences available
29148239Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.No related sentences available
29687628Proteomic Profiling Exosomes from Vascular Smooth Muscle Cell.No related sentences available
39558134Serum small extracellular vesicles-derived BST2 as a biomarker for papillary thyroid microcarcinoma promotes lymph node metastasis.No related sentences available