Protein detail

RASF3

Ras association domain-containing protein 3

Entry name
RASF3
UniProt ID
Q86WH2
EVMP confidence score
0.40
Supporting publications (n)
2
Transmembrane count
Protein classification
Predicted intracellular proteins
Basic Information
Protein Names
Ras association domain-containing protein 3
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
ENSG00000153179
Entrez Gene Symbol
RASSF3
Gene Description
Ras association domain family member 3
Chromosome
12
Position
64507001-64697564
Supporting publications (n)
2
EVMP confidence score
0.40
Fluorescence & Localization
Tissue SpecificbrainCell SpecificAdrenal medulla cellsBlood Cell SpecificNK-cellBlood Lineage SpecificNK-cellsSecretome LocationSecreted in other tissuesSecretome FunctionReceptor
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component (4)
Molecular Function (2)
Mediation Categories
Other mediation
Relations & Evidence5

Ligand-Receptor Signaling (4)

4 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPI
intracellularintracellularGO_Intercell
intracellularintracellularUniProt_location
intracellularintracellularOmniPath

Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyMass spectrometry140689422
Sequence, Structure & Domains

Sequences

Length
238
Mass
27,562
Sequence
MSSGYSSLEEDAEDFFFTARTSFFRRAPQGKPRSGQQDVEKEKETHSYLSKEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPPQTSPNSGKLSPSSNGCMNTLHISSTNTVGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKRRYTAYRQKLEEALREVWKPD
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; Synonyms=A; IsoId=Q86WH2-1; Sequence=Displayed; Name=2; Synonyms=B; IsoId=Q86WH2-2; Sequence=VSP_019353, VSP_019354
Alternative Sequence
74..90; NSNGIYTGFIKVQMELC -> STPASSQTGNIHSTCVW (in isoform 2); 91..238; Missing (in isoform 2)

Domain & Motif Annotations

Compositional Bias
38..48; Basic and acidic residues
Domain (FT)
79..186; Ras-associating; 187..234; SARAH
Region
26..48; Disordered
Clinical Relevance
Antibody (3)
CAB022664CAB034035HPA038469
Interaction Protein (4)
ENSG00000101109ENSG00000101558ENSG00000104375ENSG00000189067
Interaction Count
4
Interaction Dataset (3)
intact_biogrid_opencellbiogrid_opencellintact_biogrid
Supporting Publications2
PMIDTitleRelated sentences
38113368In-Depth Proteome Profiling of Small Extracellular Vesicles Isolated from Cancer Cell Lines and Patient Serum.No related sentences available
38207106Proteomic, Metabolomic, and Fatty Acid Profiling of Small Extracellular Vesicles from Glioblastoma Stem-Like Cells and Their Role in Tumor Heterogeneity.No related sentences available