Protein detail

RASF3

Ras association domain-containing protein 3

Entry name
RASF3
UniProt ID
EVMP score
0.38
Frequency
2
Transmembrane count
Protein classification
Predicted intracellular proteins
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Ras association domain-containing protein 3
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Entrez Gene Symbol
Gene Description
Ras association domain family member 3
Chromosome
12
Position
64507001-64697564
Frequency
2
EVMP Score
0.38
Fluorescence & Localization
Tissue SpecificbrainCell SpecificAdrenal medulla cellsBlood Cell SpecificNK-cellBlood Lineage SpecificNK-cellsSecretome LocationSecreted in other tissuesSecretome FunctionReceptor
Function & Pathway
Protein Function
Predicted intracellular proteins
Mediation Categories
Other mediation
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

4 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPINoNoNoNoNo
intracellularintracellularGO_IntercellNoNoNoNoNo
intracellularintracellularUniProt_locationNoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo

Regulatory Interaction Network

0 records.

Protein Complex Composition

0 records.

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyMass spectrometry140689422
Sequence, Structure & Domains

Sequences

Length
238
Mass
27,562
Sequence
MSSGYSSLEEDAEDFFFTARTSFFRRAPQGKPRSGQQDVEKEKETHSYLSKEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPPQTSPNSGKLSPSSNGCMNTLHISSTNTVGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKRRYTAYRQKLEEALREVWKPD
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; Synonyms=A; IsoId=Q86WH2-1; Sequence=Displayed; Name=2; Synonyms=B; IsoId=Q86WH2-2; Sequence=VSP_019353, VSP_019354
Alternative Sequence
74..90; NSNGIYTGFIKVQMELC -> STPASSQTGNIHSTCVW (in isoform 2); 91..238; Missing (in isoform 2)

3D Structural Models

Domain & Motif Annotations

Compositional Bias
38..48; Basic and acidic residues
Domain (FT)
79..186; Ras-associating; 187..234; SARAH
Region
26..48; Disordered
Clinical Relevance
Interaction Protein
ENSG00000101109ENSG00000101558ENSG00000104375ENSG00000189067
Interaction Count
4
Interaction Dataset
intact_biogrid_opencellbiogrid_opencellintact_biogrid