Protein detail
AN13B
Ankyrin repeat domain-containing protein 13B
Entry name AN13B | UniProt ID | EVMP confidence score 0.38 |
Supporting publications (n) 1 | Transmembrane count | Protein classification Predicted intracellular proteins |
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40Basic Information11
Protein Names
Ankyrin repeat domain-containing protein 13B
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
FLJ25555
Gene Description
Ankyrin repeat domain 13B
Chromosome
17
Position
29589769-29614761
Supporting publications (n)
1
EVMP confidence score
0.38
Fluorescence & Localization1
Tissue Specificlymphoid tissue
Function & Pathway6
Protein Function
Predicted intracellular proteins
Cellular Component (6)
Molecular Function
Biological Process (3)
Canonical Pathways (2)
- M277 Pid integrin a4b1 pathway
- M16 Pid insulin pathway
Mediation Categories (2)
Adhesion and uptake mediationFusion and delivery mediation
Relations & Evidence9
Ligand-Receptor Signaling (6)
6 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
| plasma_membrane | plasma_membrane | UniProt_location | No | No | No | No | No |
| plasma_membrane | plasma_membrane | OmniPath | No | No | No | No | No |
Protein Complex Composition (2)
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationDensity Gradient CentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion ChromatographyPolymer PrecipitationImmunoaffinity Capture | Mass spectrometryMass spectrometry [LTQ-FT Ultra]Mass spectrometry [QTOF] | 36 | 231615133720509834817906327954142316151338014595309150843698231235611462329441933661217230379855305857303778691838168906407486583950575634817906289865854056347522740476278941042904550530646616319416063229583334571828383215354008906732089743399406411983798237438638198379824056347534980157 |
Sequence, Structure & Domains9
Sequences
Length
626
Mass
70,205
Sequence
MIPANASARKGPEGKYPLHYLVWHNRHRELEKEVRAGQVDIEQLDPRGRTPLHLATTLGHLECARVLLAHGADVGRENRSGWTVLQEAVSTRDLELVQLVLRYRDYQRVVKRLAGIPVLLEKLRKAQDFYVEMKWEFTSWVPLVSKICPSDTYKVWKSGQNLRVDTTLLGFDHMTWQRGNRSFVFRGQDTSAVVMEIDHDRRVVYTETLALAGQDRELLLAAAQPTEEQVLSRLTAPVVTTQLDTKNISFERNKTGILGWRSEKTEMVNGYEAKVYGASNVELITRTRTEHLSEQHKGKVKGCKTPLQSFLGIAEQHGGPQNGTLITQTLSQANPTAITAEEYFNPNFELGNRDMGRPMELTTKTQKFKAKLWLCEEHPLSLCEQVAPIIDLMAVSNALFAKLRDFITLRLPPGFPVKIEIPIFHILNARITFGNLNGCDEPVPSVRGSPSSETPSPGSDSSSVSSSSSTTSCRGCEISPALFEAPRGYSMMGGQREAATRDDDDDLLQFAIQQSLLEAGSEYDQVTIWEALTNSKPGTHPMSYEGRRQDRSAPPTPQRQPAPPASVPSPRPSSGPGSGGHVFRSYDEQLRLAMELSAQEQEERRRRARQEEEELERILRLSLTEQ
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q86YJ7-1; Sequence=Displayed; Name=2; IsoId=Q86YJ7-2; Sequence=VSP_019404
Alternative Sequence
1..132; Missing (in isoform 2)
Domain & Motif Annotations
Compositional Bias
449..472; Low complexity; 554..573; Pro residues
Repeat
47..76; ANK 1; 80..109; ANK 2
Domain (FT)
503..522; UIM 1; 585..604; UIM 2; 610..626; UIM 3
Region
442..474; Disordered; 534..590; Disordered; 595..614; Disordered
Supporting Publications1
| PMID | Title | Abstract |
|---|---|---|
| 40730843 | Single urinary extracellular vesicle proteomics identifies complement receptor CD35 as a biomarker for sepsis-associated acute kidney injury. | No abstract available |