Protein detail
RASL3
RAS protein activator like-3
Entry name RASL3 | UniProt ID | EVMP score 0.38 |
Frequency 5 | Transmembrane count | Protein classification Predicted intracellular proteinsRAS pathway related proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
RAS protein activator like-3
Protein Class
Predicted intracellular proteinsRAS pathway related proteins
Protein Function
- Predicted intracellular proteins
- RAS pathway related proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
FLJ21438
Gene Description
RAS protein activator like 3
Chromosome
19
Position
15451624-15464544
Frequency
5
EVMP Score
0.38
Fluorescence & Localization
Cell SpecificDecidual stromal cellsSingle-Nuclei Brain SpecificastrocyteBlood Cell SpecificNK-cellBlood Lineage Specificdendritic cellsSecretome LocationSecreted in other tissuesSecretome FunctionTransport
Function & Pathway
Protein Function
- Predicted intracellular proteins
- RAS pathway related proteins
Cellular Component
Molecular Function
Biological Process
Reactome
Mediation Categories
Adhesion and uptake mediationFusion and delivery mediationImmune mediationReceptor-signaling mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Sequence, Structure & Domains
Sequences
Length
1,011
Mass
111,898
Sequence
MDPPSPSRTSQTQPTATSPLTSYRWHTGGGGEKAAGGFRWGRFAGWGRALSHQEPMVSTQPAPRSIFRRVLSAPPKESRTSRLRLSKALWGRHKNPPPEPDPEPEQEAPELEPEPELEPPTPQIPEAPTPNVPVWDIGGFTLLDGKLVLLGGEEEGPRRPRVGSASSEGSIHVAMGNFRDPDRMPGKTEPETAGPNQVHNVRGLLKRLKEKKKARLEPRDGPPSALGSRESLATLSELDLGAERDVRIWPLHPSLLGEPHCFQVTWTGGSRCFSCRSAAERDRWIEDLRRQFQPTQDNVEREETWLSVWVHEAKGLPRAAAGAPGVRAELWLDGALLARTAPRAGPGQLFWAERFHFEALPPARRLSLRLRGLGPGSAVLGRVALALEELDAPRAPAAGLERWFPLLGAPAGAALRARIRARRLRVLPSERYKELAEFLTFHYARLCGALEPALPAQAKEELAAAMVRVLRATGRAQALVTDLGTAELARCGGREALLFRENTLATKAIDEYMKLVAQDYLQETLGQVVRRLCASTEDCEVDPSKCPASELPEHQARLRNSCEEVFETIIHSYDWFPAELGIVFSSWREACKERGSEVLGPRLVCASLFLRLLCPAILAPSLFGLAPDHPAPGPARTLTLIAKVIQNLANRAPFGEKEAYMGFMNSFLEEHGPAMQCFLDQVAMVDVDAAPSGYQGSGDLALQLAVLHAQLCTIFAELDQTTRDTLEPLPTILRAIEEGQPVLVSVPMRLPLPPAQVHSSLSAGEKPGFLAPRDLPKHTPLISKSQSLRSVRRSESWARPRPDEERPLRRPRPVQRTQSVPVRRPARRRQSAGPWPRPKGSLSMGPAPRARPWTRDSASLPRKPSVPWQRQMDQPQDRNQALGTHRPVNKLAELQCEVAALREEQKVLSRLVESLSTQIRALTEQQEQLRGQLQDLDSRLRAGSSEFDSEHNLTSNEGHSLKNLEHRLNEMERTQAQLRDAVQSLQLSPRTRGSWSQPQPLKAPCLNGDTT
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q86YV0-1; Sequence=Displayed; Name=2; IsoId=Q86YV0-2; Sequence=VSP_033824
Alternative Sequence
944..1011; Missing (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Compositional Bias
7..22; Low complexity; 81..95; Basic residues; 100..117; Acidic residues; 118..131; Pro residues; 179..190; Basic and acidic residues; 792..808; Basic and acidic residues; 871..882; Polar residues; 987..999; Polar residues
Coiled Coil
888..988
Domain (FT)
197..293; PH; 284..404; C2; 474..682; Ras-GAP
Region
1..38; Disordered; 52..136; Disordered; 151..197; Disordered; 209..230; Disordered; 756..885; Disordered; 987..1011; Disordered
Clinical Relevance
Antibody