Protein detail
TM139
Transmembrane protein 139
Entry name TM139 | UniProt ID | EVMP confidence score 0.28 |
Supporting publications (n) 2 | Transmembrane count 1 | Protein classification Predicted membrane proteinsTransporters |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Transmembrane protein 139
Protein Class (2)
Predicted membrane proteinsTransporters
Protein Function
Transporters:Accessory Factors Involved in Transport
Transmembrane
35..55; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym
FLJ90586
Gene Description
Transmembrane protein 139
Chromosome
7
Position
143279957-143288048
Supporting publications (n)
2
EVMP confidence score
0.28
Fluorescence & Localization
Tissue Specificlymphoid tissueCell SpecificFibro-adipogenic progenitorsSingle-Nuclei Brain Specificcentral nervous system macrophageBlood Cell Specificintermediate monocyteBlood Lineage Specificdendritic cells
Function & Pathway
Protein Function
Transporters:Accessory Factors Involved in Transport
Cellular Component
Molecular Function
Biological Process (3)
Mediation Categories
Other mediation
Relations & Evidence12
Ligand-Receptor Signaling (10)
10 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| transmembrane | transmembrane | UniProt_location | |||||
| transmembrane | transmembrane | UniProt_topology | |||||
| transmembrane | transmembrane | UniProt_keyword | |||||
| transmembrane_predicted | transmembrane | OmniPath | |||||
| transmembrane | transmembrane | Ramilowski_location | |||||
| transmembrane | transmembrane | OmniPath | |||||
| transmembrane | transmembrane_predicted | Phobius | |||||
| transmembrane_phobius | transmembrane_predicted | Almen2009 | |||||
| transmembrane_sosui | transmembrane_predicted | Almen2009 | |||||
| transmembrane_tmhmm | transmembrane_predicted | Almen2009 |
Protein Complex Composition (1)
Sequence, Structure & Domains
Sequences
Length
216
Mass
23,729
Sequence
MVPMHLLGRLEKPLLLLCCASFLLGLALLGIKTDITPVAYFFLTLGGFFLFAYLLVRFLEWGLRSQLQSMQTESPGPSGNARDNEAFEVPVYEEAVVGLESQCRPQELDQPPPYSTVVIPPAPEEEQPSHPEGSRRAKLEQRRMASEGSMAQEGSPGRAPINLRLRGPRAVSTAPDLQSLAAVPTLEPLTPPPAYDVCFGHPDDDSVFYEDNWAPP
Domain & Motif Annotations
Compositional Bias
127..145; Basic and acidic residues
Region
104..163; Disordered
Supporting Publications2
| PMID | Title | Related sentences |
|---|---|---|
| 32795414 | Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers. | Among traditional exosome markers, CD9, HSPA8, ALIX, and HSP90AB1 represent pan-EVP markers, while ACTB, MSN, and RAP1B are novel pan-EVP markers. |
| 37033249 | Altered ureido protein modification profiles in seminal plasma extracellular vesicles of non-normozoospermic men. | No related sentences available |