Protein detail
SLIK4
SLIT and NTRK-like protein 4
Entry name SLIK4 | UniProt ID | EVMP confidence score 0.28 |
Supporting publications (n) 1 | Transmembrane count 1 | Protein classification Predicted membrane proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
SLIT and NTRK-like protein 4
Protein Class
Predicted membrane proteins
Transmembrane
619..639; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym
DKFZp547M2010
Gene Description
SLIT and NTRK like family member 4
Chromosome
X
Position
143622790-143636101
Supporting publications (n)
1
EVMP confidence score
0.28
Fluorescence & Localization
Tissue Specificskeletal muscleCell SpecificBergmann gliaSingle-Nuclei Brain Specificcommitted oligodendrocyte precursor
Function & Pathway
Cellular Component (2)
Molecular Function
Biological Process (3)
Reactome (3)
Mediation Categories
Other mediation
Relations & Evidence33
Ligand-Receptor Signaling (32)
32 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| receptor | receptor | OmniPath | Yes | Yes | |||
| intracellular | intracellular | ComPPI | Yes | ||||
| intracellular | intracellular | OmniPath | Yes | ||||
| cell_surface_ligand | cell_surface_ligand | CellPhoneDB | Yes | Yes | |||
| cell_surface_ligand | cell_surface_ligand | OmniPath | Yes | Yes | |||
| cell_adhesion | cell_adhesion | Cellinker | Yes | Yes | Yes | ||
| adhesion | adhesion | OmniPath | Yes | Yes | Yes | ||
| cell_adhesion | cell_adhesion | OmniPath | Yes | Yes | Yes | ||
| transmembrane | transmembrane | UniProt_location | Yes | ||||
| transmembrane | transmembrane | UniProt_topology | Yes |
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Isolation & Detection Technology (1)
Sequence, Structure & Domains
Sequences
Length
837
Mass
94,331
Sequence
MFLWLFLILSALISSTNADSDISVEICNVCSCVSVENVLYVNCEKVSVYRPNQLKPPWSNFYHLNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFRFASLTHLDIRGNRIQKLPYIGVLEHIGRVVELQLEDNPWNCSCDLLPLKAWLENMPYNIYIGEAICETPSDLYGRLLKETNKQELCPMGTGSDFDVRILPPSQLENGYTTPNGHTTQTSLHRLVTKPPKTTNPSKISGIVAGKALSNRNLSQIVSYQTRVPPLTPCPAPCFCKTHPSDLGLSVNCQEKNIQSMSELIPKPLNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAPLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNPWDCTCDLVALKLWVEKLSDGIVVKELKCETPVQFANIELKSLKNEILCPKLLNKPSAPFTSPAPAITFTTPLGPIRSPPGGPVPLSILILSILVVLILTVFVAFCLLVFVLRRNKKPTVKHEGLGNPDCGSMQLQLRKHDHKTNKKDGLSTEAFIPQTIEQMSKSHTCGLKESETGFMFSDPPGQKVVMRNVADKEKDLLHVDTRKRLSTIDELDELFPSRDSNVFIQNFLESKKEYNSIGVSGFEIRYPEKQPDKKSKKSLIGGNHSKIVVEQRKSEYFELKAKLQSSPDYLQVLEEQTALNKI
Domain & Motif Annotations
Repeat
60..81; LRR 1; 84..105; LRR 2; 108..129; LRR 3; 132..153; LRR 4; 156..177; LRR 5; 179..200; LRR 6; 378..399; LRR 7; 402..423; LRR 8; 426..447; LRR 9; 450..471; LRR 10; 474..495; LRR 11; 497..518; LRR 12
Domain (FT)
213..264; LRRCT 1; 333..375; LRRNT; 531..582; LRRCT 2
Protein Families
SLITRK family
Sequence Similarities
Belongs to the SLITRK family.
Clinical Relevance
Antibody
Supporting Publications1
| PMID | Title | Related sentences |
|---|---|---|
| 31382537 | An Insight into the Proteome of Uveal Melanoma-Derived Ectosomes Reveals the Presence of Potentially Useful Biomarkers. | No related sentences available |