Protein detail

SLIK4

SLIT and NTRK-like protein 4

Entry name
SLIK4
UniProt ID
EVMP confidence score
0.25
Supporting publications (n)
1
Transmembrane count
1
Protein classification
Predicted membrane proteins
EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information12
Protein Names
SLIT and NTRK-like protein 4
Protein Class
Predicted membrane proteins
Transmembrane
619..639; Helical
Transmembrane Count
1
Entrez Gene Symbol
Gene Synonym
DKFZp547M2010
Gene Description
SLIT and NTRK like family member 4
Chromosome
X
Position
143622790-143636101
Supporting publications (n)
1
EVMP confidence score
0.25
Fluorescence & Localization3
Tissue Specificskeletal muscleCell SpecificBergmann gliaSingle-Nuclei Brain Specificcommitted oligodendrocyte precursor
Function & Pathway6
Relations & Evidence33

Ligand-Receptor Signaling (32)

32 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
transmembrane_sosuitransmembrane_predictedAlmen2009NoNoNoYesNo
transmembrane_tmhmmtransmembrane_predictedAlmen2009NoNoNoYesNo
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Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion ChromatographyMass spectrometryWestern blottingFlow cytometry83330447832854315325607233330982631805958386070623820710639207047
Sequence, Structure & Domains7

Sequences

Length
837
Mass
94,331
Sequence
MFLWLFLILSALISSTNADSDISVEICNVCSCVSVENVLYVNCEKVSVYRPNQLKPPWSNFYHLNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFRFASLTHLDIRGNRIQKLPYIGVLEHIGRVVELQLEDNPWNCSCDLLPLKAWLENMPYNIYIGEAICETPSDLYGRLLKETNKQELCPMGTGSDFDVRILPPSQLENGYTTPNGHTTQTSLHRLVTKPPKTTNPSKISGIVAGKALSNRNLSQIVSYQTRVPPLTPCPAPCFCKTHPSDLGLSVNCQEKNIQSMSELIPKPLNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAPLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNPWDCTCDLVALKLWVEKLSDGIVVKELKCETPVQFANIELKSLKNEILCPKLLNKPSAPFTSPAPAITFTTPLGPIRSPPGGPVPLSILILSILVVLILTVFVAFCLLVFVLRRNKKPTVKHEGLGNPDCGSMQLQLRKHDHKTNKKDGLSTEAFIPQTIEQMSKSHTCGLKESETGFMFSDPPGQKVVMRNVADKEKDLLHVDTRKRLSTIDELDELFPSRDSNVFIQNFLESKKEYNSIGVSGFEIRYPEKQPDKKSKKSLIGGNHSKIVVEQRKSEYFELKAKLQSSPDYLQVLEEQTALNKI

Domain & Motif Annotations

Repeat
60..81; LRR 1; 84..105; LRR 2; 108..129; LRR 3; 132..153; LRR 4; 156..177; LRR 5; 179..200; LRR 6; 378..399; LRR 7; 402..423; LRR 8; 426..447; LRR 9; 450..471; LRR 10; 474..495; LRR 11; 497..518; LRR 12
Domain (FT)
213..264; LRRCT 1; 333..375; LRRNT; 531..582; LRRCT 2
Protein Families
SLITRK family
Sequence Similarities
Belongs to the SLITRK family.
Clinical Relevance1
Antibody
Supporting Publications1
PMIDTitleAbstract
31382537An Insight into the Proteome of Uveal Melanoma-Derived Ectosomes Reveals the Presence of Potentially Useful Biomarkers.No abstract available