Protein detail

MA7D3

MAP7 domain-containing protein 3

Entry name
MA7D3
UniProt ID
Q8IWC1
EVMP confidence score
0.28
Supporting publications (n)
1
Transmembrane count
Protein classification
Predicted intracellular proteins
Basic Information
Protein Names
MAP7 domain-containing protein 3
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
ENSG00000129680
Entrez Gene Symbol
MAP7D3
Gene Synonym
FLJ12649
Gene Description
MAP7 domain containing 3
Chromosome
X
Position
136213220-136256482
Supporting publications (n)
1
EVMP confidence score
0.28
Fluorescence & Localization
Tissue Specificbone marrowCell SpecificcDCSingle-Nuclei Brain Specificcentral nervous system macrophage
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component (4)
Molecular Function (2)
Biological Process (3)
Mediation Categories
Other mediation
Relations & Evidence6

Ligand-Receptor Signaling (4)

4 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPI
intracellularintracellularGO_Intercell
intracellularintracellularUniProt_location
intracellularintracellularOmniPath

Protein Complex Composition (1)

1 record.

Component NameComponent Gene SymbolsComponent UniProt IDStoichiometryDatabaseDatabase IDsReferences
CARD8LRIF1MAP7D3Q5T3J3Q8IWC1Q9Y2G20:0:0hu.MAP

Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyMass spectrometryWestern blottingELISA440189497335925003820710638716512
Sequence, Structure & Domains

Sequences

Length
876
Mass
98,429
Sequence
MMADGAAAGAGGSPSLRELRARMVAAANEIAKERRKQDVVNRVATHSSNIRSTFKPVIDGSMLKNDIKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKPRVTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDSEMSMDASPELSIEALPKVDLETVPKVSIVASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEAMVKASPKTSLEASMEASPKAKARDAPKKSEMDKQALIPIAKKRLSSYTECYKWSSSPENACGLPSPISTNRQIQKNCPPSPLPLISKQSPQTSFPYKIMPIQHTLSVQSASSTVKKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAATKILTELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRKTDVNASKVTETSSHDIYEEAEADNEESDKDSLNEMFPSAILNGTGSPTKFKMPFNNAKKMTHKLVFLEDGTSQVRKEPKTYFNGDLKNFRQKSMKDTSIQEVVSRPSSKRMTSHTTKTRKADETNTTSRSSAQTKSEGFHDILPKSSDTFRQ
Alternative Products
Event=Alternative splicing; Named isoforms=4; Name=1; IsoId=Q8IWC1-1; Sequence=Displayed; Name=2; IsoId=Q8IWC1-2; Sequence=VSP_028499; Name=3; IsoId=Q8IWC1-3; Sequence=VSP_028498; Name=4; IsoId=Q8IWC1-4; Sequence=VSP_045008
Alternative Sequence
1..23; MMADGAAAGAGGSPSLRELRARM -> MTSPR (in isoform 4); 179..214; ANKRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKR -> G (in isoform 3); 246..286; Missing (in isoform 2)

Domain & Motif Annotations

Compositional Bias
171..183; Polar residues; 191..211; Polar residues; 214..244; Basic and acidic residues; 425..438; Basic and acidic residues; 465..475; Basic and acidic residues; 510..521; Polar residues; 613..639; Basic and acidic residues; 680..697; Basic and acidic residues; 742..752; Acidic residues; 820..830; Polar residues; 831..842; Basic residues; 848..860; Polar residues; 861..876; Basic and acidic residues
Coiled Coil
65..144; 558..640; 689..724
Region
72..137; Disordered; 170..246; Disordered; 407..475; Disordered; 509..533; Disordered; 613..697; Disordered; 723..754; Disordered; 802..876; Disordered
Protein Families
MAP7 family
Sequence Similarities
Belongs to the MAP7 family.
Clinical Relevance
Antibody (2)
HPA035598HPA058101
Supporting Publications1
PMIDTitleRelated sentences
21630462Proteomic analysis of microvesicles derived from human colorectal cancer ascites.No related sentences available