Protein detail

CD302

CD302 antigen (C-type lectin BIMLEC) (C-type lectin domain family 13 member A) (DEC205-associated C-type lectin 1) (Type I transmembrane C-type lectin receptor DCL-1) (CD antigen CD302)

Entry name CD302	UniProt ID Q8IX05	EVMP confidence score 0.25
Supporting publications (n) 1	Transmembrane count 1	Protein classification

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40

Basic Information8

Protein Names

CD302 antigen (C-type lectin BIMLEC) (C-type lectin domain family 13 member A) (DEC205-associated C-type lectin 1) (Type I transmembrane C-type lectin receptor DCL-1) (CD antigen CD302)

Protein Function

CD markers

Transmembrane

169..189; Helical

Transmembrane Count

Ensembl

ENSG00000241399

Entrez Gene Symbol

CD302

Supporting publications (n)

EVMP confidence score

0.25

Function & Pathway5

Protein Function

CD markers

Cellular Component (5)

Molecular Function (3)

Biological Process (3)

Mediation Categories (2)

Fusion and delivery mediationImmune mediation

Relations & Evidence24

Ligand-Receptor Signaling (23)

23 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
receptor	receptor	Surfaceome	No	Yes	No	Yes	No
macrophagemannoser	receptor	Surfaceome	No	Yes	No	Yes	No
scar	receptor	Surfaceome	No	Yes	No	Yes	No
receptor	receptor	OmniPath	No	Yes	No	Yes	No
extracellular	extracellular	DGIdb	No	No	No	Yes	No
extracellular	extracellular	OmniPath	No	No	No	Yes	No
intracellular	intracellular	ComPPI	No	No	No	Yes	No
intracellular	intracellular	GO_Intercell	No	No	No	Yes	No
intracellular	intracellular	UniProt_location	No	No	No	Yes	No
intracellular	intracellular	OmniPath	No	No	No	Yes	No

Page 1 of 3Next

Isolation & Detection Technology (1)

1 record.

EV Isolation Method	Detection Method	Number of References	References
Differential UltracentrifugationUltrafiltration / Tangential Flow Filtration	Mass spectrometry	4	32489530 37786918 28986585 38321535

Sequence, Structure & Domains10

Sequences

Length

232

Mass

26,183

Sequence

MLRAALPALLLPLLGLAAAAVADCPSSTWIQFQDSCYIFLQEAIKVESIEDVRNQCTDHGADMISIHNEEENAFILDTLKKQWKGPDDILLGMFYDTDDASFKWFDNSNMTFDKWTDQDDDEDLVDTCAFLHIKTGEWKKGNCEVSSVEGTLCKTAIPYKRKYLSDNHILISALVIASTVILTVLGAIIWFLYKKHSDSRFTTVFSTAPQSPYNEDCVLVVGEENEYPVQFD

Alternative Products

Event=Alternative splicing; Named isoforms=5; Name=1; IsoId=Q8IX05-1; Sequence=Displayed; Name=4; IsoId=O60449-1; Sequence=External; Name=5; IsoId=Q8IX05-2; Sequence=VSP_044258, VSP_044259; Name=2; Synonyms=Fusion protein variant V34-2; IsoId=O60449-2; Sequence=External; Name=3; Synonyms=Fusion protein variant V33-2; IsoId=O60449-3; Sequence=External

Alternative Sequence

99..156; Missing (in isoform 5); 157; I -> V (in isoform 5)

3D Structural Models

Turn

58..60; 97..100; 133..135

Helix

49..57; 69..82

Beta Strand

24..26; 29..32; 35..40; 87..90; 92..96; 101..104; 130..132; 151..156

3D Structure

NMR spectroscopy (1)

Domain & Motif Annotations

Domain (FT)

32..152; C-type lectin

Supporting Publications1

PMID	Title	Abstract
27605433	Secreted primary human malignant mesothelioma exosome signature reflects oncogenic cargo.	No abstract available