Protein detail

CD302

CD302 antigen (C-type lectin BIMLEC) (C-type lectin domain family 13 member A) (DEC205-associated C-type lectin 1) (Type I transmembrane C-type lectin receptor DCL-1) (CD antigen CD302)

Entry name CD302	UniProt ID Q8IX05	EVMP confidence score 0.25
Supporting publications (n) 1	Transmembrane count 1	Protein classification

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40

Basic Information8

Protein Names

CD302 antigen (C-type lectin BIMLEC) (C-type lectin domain family 13 member A) (DEC205-associated C-type lectin 1) (Type I transmembrane C-type lectin receptor DCL-1) (CD antigen CD302)

Protein Function

CD markers

Transmembrane

169..189; Helical

Transmembrane Count

Ensembl

ENSG00000241399

Entrez Gene Symbol

CD302

Supporting publications (n)

EVMP confidence score

0.25

Function & Pathway5

Protein Function

CD markers

Cellular Component (5)

Molecular Function (3)

Biological Process (3)

Mediation Categories (2)

Fusion and delivery mediationImmune mediation

Relations & Evidence24

Ligand-Receptor Signaling (23)

23 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
cell_surface	cell_surface	Surfaceome	No	No	No	Yes	No
cell_surface	cell_surface	OmniPath	No	No	No	Yes	No
transmembrane	transmembrane_predicted	Phobius	No	No	No	Yes	No

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Isolation & Detection Technology (1)

1 record.

EV Isolation Method	Detection Method	Number of References	References
Differential UltracentrifugationUltrafiltration / Tangential Flow Filtration	Mass spectrometry	4	32489530 37786918 28986585 38321535

Sequence, Structure & Domains10

Sequences

Length

232

Mass

26,183

Sequence

MLRAALPALLLPLLGLAAAAVADCPSSTWIQFQDSCYIFLQEAIKVESIEDVRNQCTDHGADMISIHNEEENAFILDTLKKQWKGPDDILLGMFYDTDDASFKWFDNSNMTFDKWTDQDDDEDLVDTCAFLHIKTGEWKKGNCEVSSVEGTLCKTAIPYKRKYLSDNHILISALVIASTVILTVLGAIIWFLYKKHSDSRFTTVFSTAPQSPYNEDCVLVVGEENEYPVQFD

Alternative Products

Event=Alternative splicing; Named isoforms=5; Name=1; IsoId=Q8IX05-1; Sequence=Displayed; Name=4; IsoId=O60449-1; Sequence=External; Name=5; IsoId=Q8IX05-2; Sequence=VSP_044258, VSP_044259; Name=2; Synonyms=Fusion protein variant V34-2; IsoId=O60449-2; Sequence=External; Name=3; Synonyms=Fusion protein variant V33-2; IsoId=O60449-3; Sequence=External

Alternative Sequence

99..156; Missing (in isoform 5); 157; I -> V (in isoform 5)

3D Structural Models

Turn

58..60; 97..100; 133..135

Helix

49..57; 69..82

Beta Strand

24..26; 29..32; 35..40; 87..90; 92..96; 101..104; 130..132; 151..156

3D Structure

NMR spectroscopy (1)

Domain & Motif Annotations

Domain (FT)

32..152; C-type lectin

Supporting Publications1

PMID	Title	Abstract
27605433	Secreted primary human malignant mesothelioma exosome signature reflects oncogenic cargo.	No abstract available