Protein detail

PDZD9

PDZ domain-containing protein 9

Entry name PDZD9	UniProt ID Q8IXQ8	EVMP confidence score 0.38
Supporting publications (n) 1	Transmembrane count	Protein classification

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40

Basic Information6

Protein Names

PDZ domain-containing protein 9

Protein Function

Predicted intracellular proteins

Ensembl

ENSG00000155714

Entrez Gene Symbol

PDZD9

Supporting publications (n)

EVMP confidence score

0.38

Fluorescence & Localization3

Cell SpecificOligodendrocytesSingle-Nuclei Brain Specificoligodendrocyte

Function & Pathway3

Protein Function

Predicted intracellular proteins

Biological Process (3)

Mediation Categories

Other mediation

Relations & Evidence3

Ligand-Receptor Signaling (2)

2 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
intracellular	intracellular	ComPPI	No	No	No	No	No
intracellular	intracellular	OmniPath	No	No	No	No	No

Isolation & Detection Technology (1)

1 record.

EV Isolation Method	Detection Method	Number of References	References
Differential UltracentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion Chromatography	Mass spectrometryWestern blottingFlow cytometryMORPH	5	36797805 37786918 28986585 38321535 32089743

Sequence, Structure & Domains6

Sequences

Length

264

Mass

29,904

Sequence

MQKASHKNKKERGVSNKVKTSVHNLSKTQQTKLTVGSLGLGLIIIQHGPYLQITHLIRKGAAANDGKLQPGDVLISVGHANVLGYTLREFLQLLQHITIGTVLQIKVYRDFINIPEEWQEIYDLIPEAKFPVTSTPKKIELAKDESFTSSDDNENVDLDKRLQYYRYPWSTVHHPARRPISISRDWHGYKKKNHTISVGKDINCDVMIHRDDKKEVRAPSPYWIMVKQDNESSSSSTSSTSDAFWLEDCAQVEEGKAQLVSKVG

Alternative Products

Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q8IXQ8-1; Sequence=Displayed; Name=2; IsoId=Q8IXQ8-2; Sequence=VSP_022286, VSP_022287; Name=3; IsoId=Q8IXQ8-3; Sequence=VSP_053798

Alternative Sequence

1..62; Missing (in isoform 2); 11..70; Missing (in isoform 3); 63..70; ANDGKLQP -> MAEGEEEG (in isoform 2)

Domain & Motif Annotations

Domain (FT)

30..109; PDZ

Supporting Publications1

PMID	Title	Abstract
27863537	High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources.	No abstract available