Protein detail

DDIAS

DNA damage-induced apoptosis suppressor protein (Nitric oxide-inducible gene protein)

Entry name
DDIAS
UniProt ID
Q8IXT1
EVMP confidence score
0.53
Supporting publications (n)
4
Transmembrane count
Protein classification
Predicted intracellular proteins
Basic Information
Protein Names
DNA damage-induced apoptosis suppressor protein (Nitric oxide-inducible gene protein)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
ENSG00000165490
Entrez Gene Symbol
DDIAS
Gene Synonym (4)
C11orf82FLJ25416FLJ38838noxin
Gene Description
DNA damage induced apoptosis suppressor
Chromosome
11
Position
82899975-82958277
Supporting publications (n)
4
EVMP confidence score
0.53
Fluorescence & Localization
DDIAS fluorescence
Cell SpecificEsophageal apical cells
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component (3)
Molecular Function
GO:0003674 molecular_function
Biological Process (3)
Mediation Categories
Other mediation
Relations & Evidence6

Ligand-Receptor Signaling (4)

4 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPI
intracellularintracellularGO_Intercell
intracellularintracellularUniProt_location
intracellularintracellularOmniPath

Regulatory Interaction Network (1)

1 record.

Source Protein SymbolSource UniProt IDTarget Protein SymbolTarget UniProt IDIs DirectedIs StimulationIs InhibitionDatabaseReferences
CHIPQ9UNE7DDIASQ8IXT1YesYesLit-BM-17SIGNORLit-BM-17:28079882SIGNOR:28079882

Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Mass spectrometry0
Sequence, Structure & Domains

Sequences

Length
998
Mass
111,616
Sequence
MNRRRKFLLASVLALQNSSFIYPSCQKCFSRIILVSKRSNCPKCGSTGESGNANYRYKLSLKVAESNKLFVITVFGSCLDTFFGLTATGLHRYIQDPNKIPETLDNDTTQNLLTKAVETCFVGQSFIFGVTNFENQPGQGSDASNFLQQCSDHKRKAKALVACQIVLPDPGIAGFTVIDYFHQLLQTFNFRKLQCDSQAPNNHLLALDHSNSDLSSIYTSDSTSDFFKSCSKDTFSKFWQPSLEFTCIVSQLTDNDDFSASEQSKAFGTLQQNRKSISIAEATGSSSCHDPIQDSWSLVSYMDKKSTAEKLGKELGLQAKELSAVHSSHHEIGVNDSNLFSLEMREPLESSNTKSFHSAVEIKNRSQHELPCFQHHGIDTPTSLQKRSACCPPSLLRLEETASSSQDGDPQIWDDLPFSESLNKFLAVLESEIAVTQADVSSRKHHVDNDIDKFHADHSRLSVTPQRTTGALHTPPIALRSSQVIVKANCSKDDFLFNCKGNLSPSVEKESQPDNKVEAVSVNHNGRDMSEYFLPNPYLSALSSSSKDLETIVTLKKTIRISPHRESDHSSLNNKYLNGCGEISVSEMNEKLTTLCYRKYNDVSDLCKLENKQYCRWSKNQDDSFTICRKLTYPLETLCNSPNRSTNTLKEMPWGHINNNVTQSYSIGYEGSYDASADLFDDIAKEMDIATEITKKSQDILLKWGTSLAESHPSESDFSLRSLSEDFIQPSQKLSLQSLSDSRHSRTCSPTPHFQSDSEYNFENSQDFVPCSQSTPISGFHQTRIHGINRAFKKPVFYSDLDGNYEKIRIFPENDKQQASPSCPKNIKTPSQKIRSPIVSGVSQPDVFNHYPFAECHETDSDEWVPPTTQKIFPSDMLGFQGIGLGKCLAAYHFPDQQELPRKKLKHIRQGTNKGLIKKKLKNMLAAVVTKKKTHKYNCKSSGWISKCPDIQVLAAPQLHPILGPDSCSEVKCCLPFSEKGPPSVCETRSAWSPELFS
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8IXT1-1; Sequence=Displayed; Name=2; IsoId=Q8IXT1-2; Sequence=VSP_029606, VSP_029607
Alternative Sequence
171..178; GIAGFTVI -> ATQDAKTK (in isoform 2); 179..998; Missing (in isoform 2)

Domain & Motif Annotations

Compositional Bias
817..834; Polar residues
Region
815..834; Disordered
Clinical Relevance
Antibody (2)
HPA038540HPA038541
Supporting Publications4
PMIDTitleRelated sentences
33709510Unbiased proteomic profiling of host cell extracellular vesicle composition and dynamics upon HIV-1 infection.No related sentences available
37922300Proteomic profiling of urinary extracellular vesicles differentiates breast cancer patients from healthy women.No related sentences available
38576002Therapy-induced senescent tumor cell-derived extracellular vesicles promote colorectal cancer progression through SERPINE1-mediated NF-κB p65 nuclear translocation.No related sentences available
40098346Toward Identification of Markers for Brain-Derived Extracellular Vesicles in Cerebrospinal Fluid: A Large-Scale, Unbiased Analysis Using Proximity Extension Assays.No related sentences available