Protein detail

T183A

Transmembrane protein 183A

Entry name
T183A
UniProt ID
EVMP score
0.50
Frequency
1
Transmembrane count
1
Protein classification
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Transmembrane protein 183A
Transmembrane
300..320; Helical
Transmembrane Count
1
Entrez Gene Symbol
Frequency
1
EVMP Score
0.50
Fluorescence & Localization
Tissue SpecifictestisCell SpecificEarly spermatidsSingle-Nuclei Brain Specificchoroid plexus epithelial cell
Function & Pathway
Molecular Function
Canonical Pathways
  • M137 Pid vegf vegfr pathway
  • M226 Pid vegfr1 pathway
Mediation Categories
Other mediation
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

11 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
transmembrane_tmhmmtransmembrane_predictedAlmen2009NoNoNoNoNo
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Regulatory Interaction Network

0 records.

Protein Complex Composition

0 records.

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyWestern blottingELISA24078452937922300
Sequence, Structure & Domains

Sequences

Length
376
Mass
42,826
Sequence
MARGPGPLGRPRPDTVAMPKRGKRLKFRAHDACSGRVTVADYANSDPAVVRSGRVKKAVANAVQQEVKSLCGLEASQVPAEEALSGAGEPCDIIDSSDEMDAQEESIHERTVSRKKKSKRHKEELDGAGGEEYPMDIWLLLASYIRPEDIVNFSLICKNAWTVTCTAAFWTRLYRRHYTLDASLPLRLRPESMEKLRCLRACVIRSLYHMYEPFAARISKNPAIPESTPSTLKNSKCLLFWCRKIVGNRQEPMWEFNFKFKKQSPRLKSKCTGGLQPPVQYEDVHTNPDQDCCLLQVTTLNFIFIPIVMGMIFTLFTINVSTDMRHHRVRLVFQDSPVHGGRKLRSEQGVQVILDPVHSVRLFDWWHPQYPFSLRA
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8IXX5-1; Sequence=Displayed; Name=2; IsoId=Q8IXX5-2; Sequence=VSP_015084
Alternative Sequence
237..376; Missing (in isoform 2)

3D Structural Models

Domain & Motif Annotations

Region
1..20; Disordered; 100..127; Disordered
Protein Families
TMEM183 family
Sequence Similarities
Belongs to the TMEM183 family.
Clinical Relevance