Protein detail

NRSN1

Neurensin-1 (Neuro-p24) (Vesicular membrane protein of 24 kDa) (Vesicular membrane protein p24)

Entry name
NRSN1
UniProt ID
Q8IZ57
EVMP confidence score
0.40
Supporting publications (n)
1
Transmembrane count
2
Protein classification
Predicted intracellular proteinsPredicted membrane proteinsTransporters
Basic Information
Protein Names
Neurensin-1 (Neuro-p24) (Vesicular membrane protein of 24 kDa) (Vesicular membrane protein p24)
Protein Class (3)
Predicted intracellular proteinsPredicted membrane proteinsTransporters
Protein Function (2)
  • Predicted intracellular proteins
  • Transporters:Accessory Factors Involved in Transport
Transmembrane
66..86; Helical; 120..140; Helical
Transmembrane Count
2
Ensembl
ENSG00000152954
Entrez Gene Symbol
NRSN1
Gene Synonym (2)
p24VMP
Gene Description
Neurensin 1
Chromosome
6
Position
24126186-24154900
Supporting publications (n)
1
EVMP confidence score
0.40
Fluorescence & Localization
NRSN1 fluorescence
Function & Pathway
Protein Function (2)
  • Predicted intracellular proteins
  • Transporters:Accessory Factors Involved in Transport
Cellular Component (6)
Molecular Function
GO:0005515 protein binding
Biological Process (3)
Mediation Categories
Fusion and delivery mediation
Relations & Evidence22

Ligand-Receptor Signaling (20)

20 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
receptorreceptorCellTalkDBYes
receptorreceptorRamilowski2015Yes
receptorreceptorLRdbYes
receptorreceptorBaccin2019Yes
receptorreceptorOmniPathYes
intracellularintracellularComPPI
intracellularintracellularGO_Intercell
intracellularintracellularOmniPath
transmembranetransmembraneUniProt_location
transmembranetransmembraneUniProt_topology
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Protein Complex Composition (1)

1 record.

Component NameComponent Gene SymbolsComponent UniProt IDStoichiometryDatabaseDatabase IDsReferences
TMP21-P24 complexNRSN1TMED10P49755Q8IZ571:1CompleatCompleat:HC35816641999

Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyMass spectrometryR SequencingFlow cytometry423161513268019193663540038490958
Sequence, Structure & Domains

Sequences

Length
195
Mass
21,475
Sequence
MSSCSNVCGSRQAQAAAEGGYQRYGVRSYLHQFYEDCTASIWEYEDDFQIQRSPNRWSSVFWKVGLISGTVFVILGLTVLAVGFLVPPKIEAFGEADFVVVDTHAVQFNSALDMYKLAGAVLFCIGGTSMAGCLLMSVFVKSYSKEEKFLQQKFKERIADIKAHTQPVTKAPGPGETKIPVTLSRVQNVQPLLAT

Domain & Motif Annotations

Protein Families
VMP family
Sequence Similarities
Belongs to the VMP family.
Clinical Relevance
Antibody (2)
HPA019681HPA061006
Supporting Publications1
PMIDTitleRelated sentences
32384937Alzheimer's disease progression characterized by alterations in the molecular profiles and biogenesis of brain extracellular vesicles.No related sentences available