Protein detail

TMM61

Transmembrane protein 61

Entry name TMM61	UniProt ID Q8N0U2	EVMP confidence score 0.50
Supporting publications (n) 1	Transmembrane count 2	Protein classification Predicted membrane proteins

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40

Basic Information11

Protein Names

Transmembrane protein 61

Protein Class

Predicted membrane proteins

Transmembrane

18..38; Helical; 69..89; Helical

Transmembrane Count

Ensembl

ENSG00000143001

Entrez Gene Symbol

TMEM61

Gene Description

Transmembrane protein 61

Chromosome

Position

54980628-54992288

Supporting publications (n)

EVMP confidence score

0.50

Fluorescence & Localization4

Cell SpecificBergmann gliaSingle-Nuclei Brain SpecificastrocyteSecretome LocationIntracellular and membraneSecretome FunctionCell adhesion

Function & Pathway5

Cellular Component

GO:0016020 membrane

Molecular Function

GO:0005515 protein binding

Biological Process (3)

Canonical Pathways

M269 Pid ras pathway

Mediation Categories

Other mediation

Relations & Evidence7

Ligand-Receptor Signaling (6)

6 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
transmembrane	transmembrane	UniProt_location	No	No	No	No	No
transmembrane	transmembrane	UniProt_topology	No	No	No	No	No
transmembrane	transmembrane	UniProt_keyword	No	No	No	No	No
transmembrane	transmembrane	Ramilowski_location	No	No	No	No	No
transmembrane	transmembrane	OmniPath	No	No	No	No	No
transmembrane	transmembrane_predicted	Phobius	No	No	No	No	No

Isolation & Detection Technology (1)

1 record.

EV Isolation Method	Detection Method	Number of References	References
Differential Ultracentrifugation	Mass spectrometry	3	36797805 39766158 33919183

Sequence, Structure & Domains4

Sequences

Length

210

Mass

22,170

Sequence

MALPQMCDGSHLASTLRYCMTVSGTVVLVAGTLCFAWWSEGDATAQPGQLAPPTEYPVPEGPSPLLRSVSFVCCGAGGLLLLIGLLWSVKASIPGPPRWDPYHLSRDLYYLTVESSEKESCRTPKVVDIPTYEEAVSFPVAEGPPTPPAYPTEEALEPSGSRDALLSTQPAWPPPSYESISLALDAVSAETTPSATRSCSGLVQTARGGS

Domain & Motif Annotations

Region

140..172; Disordered

Clinical Relevance1

Antibody (2)

HPA030614 HPA057087

Supporting Publications1

PMID	Title	Abstract
38795909	Proteomic profile of tissue-derived extracellular vesicles from benign odontogenic lesions.	No abstract available