Protein detail
LYPD1
Ly6/PLAUR domain-containing protein 1 (Putative HeLa tumor suppressor) (PHTS)
Protein symbol LYPD1 | UniProt ID | EVMP score 0.38 |
Frequency 1 | Transmembrane count | Protein classification |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Ly6/PLAUR domain-containing protein 1 (Putative HeLa tumor suppressor) (PHTS)
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Cell SpecificCytotrophoblasts
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Reactome
Mediation Categories
Metabolism mediationReceptor-signaling mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
12 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| extracellular | extracellular | OmniPath | No | No | No | No | No |
| ly6_plaur | receptor_regulator | OmniPath | Yes | No | No | No | No |
| receptor_regulator | receptor_regulator | OmniPath | Yes | No | No | No | No |
| transmembrane_predicted | transmembrane | OmniPath | No | No | No | No | No |
| transmembrane | transmembrane | GO_Intercell | No | No | No | No | No |
| transmembrane | transmembrane | OmniPath | No | No | No | No | No |
| plasma_membrane | plasma_membrane | UniProt_location | No | No | No | No | No |
| plasma_membrane | plasma_membrane | OmniPath | No | No | No | No | No |
| cell_surface | cell_surface | Surfaceome | No | No | No | No | No |
| cell_surface | cell_surface | OmniPath | No | No | No | No | No |
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Regulatory Interaction Network
0 records.
Protein Complex Composition
Sequence, Structure & Domains
Sequences
Length
141
Mass
15,240
Sequence
MWVLGIAATFCGLFLLPGFALQIQCYQCEEFQLNNDCSSPEFIVNCTVNVQDMCQKEVMEQSAGIMYRKSCASSAACLIASAGYQSFCSPGKLNSVCISCCNTPLCNGPRPKKRGSSASALRPGLRTTILFLKLALFSAHC
Alternative Products
Event=Alternative splicing; Named isoforms=4; Name=1; IsoId=Q8N2G4-1; Sequence=Displayed; Name=2; IsoId=Q8N2G4-2; Sequence=VSP_021584; Name=3; IsoId=Q8N2G4-3; Sequence=VSP_021583; Name=4; IsoId=Q8N2G4-4; Sequence=VSP_046981
Alternative Sequence
1..52; Missing (in isoform 4); 1..5; MWVLG -> MQAPRAAPAAPLSYDRRLRGS (in isoform 3); 1; M -> MQAPRAAPAAPLSYDRRPRDSGRM (in isoform 2)
3D Structural Models
Helix
74..82
Beta Strand
33..35; 42..44; 48..60; 65..73; 97..103
3D Structure
NMR spectroscopy (1)
Domain & Motif Annotations
Domain (FT)
25..107; UPAR/Ly6