Protein detail
TM252
Transmembrane protein 252
Entry name TM252 | UniProt ID | EVMP confidence score 0.28 |
Supporting publications (n) 3 | Transmembrane count 2 | Protein classification Predicted membrane proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Transmembrane protein 252
Protein Class
Predicted membrane proteins
Transmembrane
8..28; Helical; 40..60; Helical
Transmembrane Count
2
Ensembl
Entrez Gene Symbol
Gene Synonym (2)
C9orf71MGC34760
Gene Description
Transmembrane protein 252
Chromosome
9
Position
68536580-68540883
Supporting publications (n)
3
EVMP confidence score
0.28
Fluorescence & Localization
Tissue SpecificbrainCell SpecificBrain excitatory neuronsSingle-Nuclei Brain Specificeccentric medium spiny neuron
Function & Pathway
Cellular Component
Molecular Function
Biological Process (3)
Mediation Categories
Other mediation
Relations & Evidence7
Ligand-Receptor Signaling (6)
6 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| transmembrane | transmembrane | UniProt_location | |||||
| transmembrane | transmembrane | UniProt_topology | |||||
| transmembrane | transmembrane | UniProt_keyword | |||||
| transmembrane | transmembrane | Ramilowski_location | |||||
| transmembrane | transmembrane | OmniPath | |||||
| transmembrane | transmembrane_predicted | Phobius |
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation | Western blottingFlow cytometry | 1 | 38321535 |
Sequence, Structure & Domains
Sequences
Length
170
Mass
18,703
Sequence
MQNRTGLILCALALLMGFLMVCLGAFFISWGSIFDCQGSLIAAYLLLPLGFVILLSGIFWSNYRQVTESKGVLRHMLRQHLAHGALPVATVDRPDFYPPAYEESLEVEKQSCPAEREASGIPPPLYTETGLEFQDGNDSHPEAPPSYRESIAGLVVTAISEDAQRRGQEC
Domain & Motif Annotations
Region
112..147; Disordered
Supporting Publications3
| PMID | Title | Related sentences |
|---|---|---|
| 30608700 | Quantitative Proteomic Analysis of Small and Large Extracellular Vesicles (EVs) Reveals Enrichment of Adhesion Proteins in Small EVs. | No related sentences available |
| 38731868 | The Deep Proteomics Approach Identified Extracellular Vesicular Proteins Correlated to Extracellular Matrix in Type One and Two Endometrial Cancer. | No related sentences available |
| 40098346 | Toward Identification of Markers for Brain-Derived Extracellular Vesicles in Cerebrospinal Fluid: A Large-Scale, Unbiased Analysis Using Proximity Extension Assays. | No related sentences available |