Protein detail
CCYL1
Cyclin-Y-like protein 1
Entry name CCYL1 | UniProt ID | EVMP confidence score 0.53 |
Supporting publications (n) 5 | Transmembrane count | Protein classification Predicted intracellular proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Cyclin-Y-like protein 1
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
FLJ40432
Gene Description
Cyclin Y like 1
Chromosome
2
Position
207711540-207761839
Supporting publications (n)
5
EVMP confidence score
0.53
Fluorescence & Localization
Cell SpecificBrain excitatory neuronsSingle-Nuclei Brain Specificchoroid plexus epithelial cell
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function (2)
Biological Process (3)
Mediation Categories
Receptor-signaling mediation
Relations & Evidence5
Ligand-Receptor Signaling (4)
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | |||||
| intracellular | intracellular | OmniPath | |||||
| plasma_membrane | plasma_membrane | UniProt_location | |||||
| plasma_membrane | plasma_membrane | OmniPath |
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation | Mass Spectrometry | 1 | 33709510 |
Sequence, Structure & Domains
Sequences
Length
359
Mass
40,705
Sequence
MGNTLTCCVSPNASPKLGRRAGSAELYCASDIYEAVSGDAVAVAPAVVEPAELDFGEGEGHHLQHISDREMPEDLALESNPSDHPRASTIFLSKSQTDVREKRKSNHLNHVSPGQLTKKYSSCSTIFLDDSTVSQPNLRTTVKCVTLAIYYHIKNRDANRSLDIFDERSHPLTREKVPEEYFKHDPEHKFIYRFVRTLFSAAQLTAECAIVTLVYLERLLTYAEIDICPTNWKRIVLGAILLASKVWDDQAVWNVDYCQILKDITVEDMNEMERHFLELLQFNINVPASVYAKYYFDLRSLADDNNLNFLFAPLSKERAQNLEAISRLCEDKDLCRAAMRRSFSADNFIGIQRSKAILS
Alternative Products
Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q8N7R7-1; Sequence=Displayed; Name=2; IsoId=Q8N7R7-2; Sequence=VSP_029134; Name=3; IsoId=Q8N7R7-3; Sequence=VSP_029133
Alternative Sequence
1..70; Missing (in isoform 3); 111..173; VSPGQLTKKYSSCSTIFLDDSTVSQPNLRTTVKCVTLAIYYHIKNRDANRSLDIFDERSHPLT -> CDLSNILPHKEQ (in isoform 2)
Domain & Motif Annotations
Domain (FT)
145..267; Cyclin N-terminal
Protein Families (2)
- Cyclin family
- Cyclin Y subfamily
Sequence Similarities
Belongs to the cyclin family. Cyclin Y subfamily.
Clinical Relevance
Antibody
Interaction Protein
ENSG00000102225
Interaction Count
1
Interaction Dataset
intact_biogrid_bioplex
Supporting Publications5
| PMID | Title | Related sentences |
|---|---|---|
| 32560723 | T2 and T17 cytokines alter the cargo and function of airway epithelium-derived extracellular vesicles. | No related sentences available |
| 36064647 | Systemic proteomics and miRNA profile analysis of exosomes derived from human pluripotent stem cells. | No related sentences available |
| 36146834 | Human Cytomegalovirus Modifies Placental Small Extracellular Vesicle Composition to Enhance Infection of Fetal Neural Cells In Vitro. | No related sentences available |
| 38113368 | In-Depth Proteome Profiling of Small Extracellular Vesicles Isolated from Cancer Cell Lines and Patient Serum. | No related sentences available |
| 40189497 | Small extracellular vesicle-based one-step high-throughput microfluidic platform for epithelial ovarian cancer diagnosis. | No related sentences available |