Protein detail
PDCD7
Programmed cell death protein 7 (ES18) (hES18)
Entry name PDCD7 | UniProt ID | EVMP confidence score 0.38 |
Supporting publications (n) 2 | Transmembrane count | Protein classification Essential proteinsPredicted intracellular proteins |
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40Basic Information11
Protein Names
Programmed cell death protein 7 (ES18) (hES18)
Protein Class (2)
Essential proteinsPredicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym (3)
59KES18HES18
Gene Description
Programmed cell death 7
Chromosome
15
Position
65117379-65133808
Supporting publications (n)
2
EVMP confidence score
0.38
Fluorescence & Localization6
Tissue Specificskeletal muscleCell SpecificAlveolar cells type 1Single-Nuclei Brain Specifichippocampal CA4Secretome LocationIntracellular and membraneSecretome FunctionImmunity
Function & Pathway5
Protein Function
Predicted intracellular proteins
Cellular Component (2)
Biological Process (3)
Reactome (4)
Mediation Categories
Other mediation
Relations & Evidence16
Ligand-Receptor Signaling (4)
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Protein Complex Composition (11)
11 records.
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Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Mass spectrometryR Sequencing | 0 |
Sequence, Structure & Domains9
Sequences
Length
485
Mass
54,700
Sequence
MALPPFFGQGRPGPPPPQPPPPAPFGCPPPPLPSPAFPPPLPQRPGPFPGASAPFLQPPLALQPRASAEASRGGGGAGAFYPVPPPPLPPPPPQCRPFPGTDAGERPRPPPPGPGPPWSPRWPEAPPPPADVLGDAALQRLRDRQWLEAVFGTPRRAGCPVPQRTHAGPSLGEVRARLLRALRLVRRLRGLSQALREAEADGAAWVLLYSQTAPLRAELAERLQPLTQAAYVGEARRRLERVRRRRLRLRERAREREAEREAEAARAVEREQEIDRWRVKCVQEVEEKKREQELKAAADGVLSEVRKKQADTKRMVDILRALEKLRKLRKEAAARKGVCPPASADETFTHHLQRLRKLIKKRSELYEAEERALRVMLEGEQEEERKRELEKKQRKEKEKILLQKREIESKLFGDPDEFPLAHLLEPFRQYYLQAEHSLPALIQIRHDWDQYLVPSDHPKGNFVPQGWVLPPLPSNDIWATAVKLH
3D Structural Models
Turn
229..233
Helix
172..197; 198..200; 202..223; 224..228; 235..285; 292..331; 333..336; 341..383
3D Structure
Electron microscopy (5)
Domain & Motif Annotations
Compositional Bias
12..48; Pro residues; 49..71; Low complexity; 82..96; Pro residues; 109..130; Pro residues
Coiled Coil
232..335; 362..411
Region
1..133; Disordered
Clinical Relevance1
Antibody
Supporting Publications2
| PMID | Title | Abstract |
|---|---|---|
| 27470641 | Phosphoproteome Characterization of Human Colorectal Cancer SW620 Cell-Derived Exosomes and New Phosphosite Discovery for C-HPP. | No abstract available |
| 30865381 | Surfaceome of Exosomes Secreted from the Colorectal Cancer Cell Line SW480: Peripheral and Integral Membrane Proteins Analyzed by Proteolysis and TX114. | No abstract available |