Protein detail
AQP11
Aquaporin-11 (AQP-11)
Entry name AQP11 | UniProt ID | EVMP confidence score 0.53 |
Supporting publications (n) 1 | Transmembrane count 6 | Protein classification |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Aquaporin-11 (AQP-11)
Protein Function
Transporters:Transporter channels and pores
Transmembrane
15..35; Helical; Name=1; 42..62; Helical; Name=2; 75..95; Helical; Name=3; 164..184; Helical; Name=4; 195..215; Helical; Name=5; 235..255; Helical; Name=6
Transmembrane Count
6
Ensembl
Entrez Gene Symbol
Supporting publications (n)
1
EVMP confidence score
0.53
Fluorescence & Localization
Tissue Specificchoroid plexusCell SpecificChoroid plexus epithelial cellsSingle-Nuclei Brain Specificchoroid plexus epithelial cell
Function & Pathway
Protein Function
Transporters:Transporter channels and pores
Cellular Component (8)
Molecular Function (4)
Biological Process (3)
Reactome (3)
Mediation Categories
Fusion and delivery mediation
Relations & Evidence21
Ligand-Receptor Signaling (20)
20 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| ion_channel | ion_channel | OmniPath | Yes | ||||
| transmembrane | transmembrane | UniProt_location | |||||
| transmembrane | transmembrane | UniProt_topology | |||||
| transmembrane | transmembrane | UniProt_keyword | |||||
| transmembrane | transmembrane | Ramilowski_location | |||||
| transmembrane | transmembrane | OmniPath | |||||
| plasma_membrane | plasma_membrane | UniProt_location | |||||
| plasma_membrane | plasma_membrane | OmniPath | |||||
| receptor | receptor | scConnect | Yes | ||||
| transmembrane | transmembrane_predicted | Phobius |
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Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationSize Exclusion Chromatography | Western blottingMass spectrometryFACSWestern blotting|FACS|Mass spectrometryImmunoelectron MicroscopyMass spectrometry|Western blottingWestern blotting|FACSImmunoelectron microscopyMass spectrometry [LTQ-FT Ultra]|Western blottingMass spectrometry [QTOF]Flow cytometric alysis|Mass spectrometryFlow cytometryImmuno-EM | 1 | 23260141 |
Sequence, Structure & Domains
Sequences
Length
271
Mass
30,203
Sequence
MSPLLGLRSELQDTCTSLGLMLSVVLLMGLARVVARQQLHRPVAHAFVLEFLATFQLCCCTHELQLLSEQHPAHPTWTLTLVYFFSLVHGLTLVGTSSNPCGVMMQMMLGGMSPETGAVRLLAQLVSALCSRYCTSALWSLGLTQYHVSERSFACKNPIRVDLLKAVITEAVCSFLFHSALLHFQEVRTKLRIHLLAALITFLVYAGGSLTGAVFNPALALSLHFMCFDEAFPQFFIVYWLAPSLGILLMILMFSFFLPWLHNNHTINKKE
Domain & Motif Annotations
Motif
99..101; NPC; 216..218; NPA
Domain (CC)
The NPC motif is essential for oligomerization and water permeability function.
Protein Families (2)
- MIP/aquaporin (TC 1.A.8) family
- AQP11/AQP12 subfamily
Sequence Similarities
Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
Supporting Publications1
| PMID | Title | Related sentences |
|---|---|---|
| 27487081 | Comparative Proteomic Analysis of Extracellular Vesicles Isolated by Acoustic Trapping or Differential Centrifugation. | No related sentences available |