Protein detail
CLC1A
C-type lectin domain family 1 member A (C-type lectin-like receptor 1) (CLEC-1)
Entry name CLC1A | UniProt ID | EVMP confidence score 0.53 |
Supporting publications (n) 2 | Transmembrane count 1 | Protein classification |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
C-type lectin domain family 1 member A (C-type lectin-like receptor 1) (CLEC-1)
Protein Function
Predicted intracellular proteins
Transmembrane
53..73; Helical; Signal-anchor for type II membrane protein
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Supporting publications (n)
2
EVMP confidence score
0.53
Fluorescence & Localization
Tissue SpecificlungCell SpecificAlveolar cells type 1Single-Nuclei Brain Specificendothelial cell
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function (3)
Biological Process (3)
Canonical Pathways
M142 Pid ajdiss 2pathway
Mediation Categories
Other mediation
Relations & Evidence22
Ligand-Receptor Signaling (21)
21 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| receptor | receptor | Surfaceome | Yes | ||||
| scavenger | receptor | Almen2009 | Yes | ||||
| class_e | receptor | Surfaceome | Yes | ||||
| scar | receptor | Surfaceome | Yes | ||||
| receptor | receptor | OmniPath | Yes | ||||
| transmembrane | transmembrane | UniProt_location | |||||
| transmembrane | transmembrane | UniProt_topology | |||||
| transmembrane | transmembrane | UniProt_keyword | |||||
| transmembrane_predicted | transmembrane | OmniPath | |||||
| transmembrane | transmembrane | GO_Intercell |
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Sequence, Structure & Domains
Sequences
Length
280
Mass
31,952
Sequence
MQAKYSSTRDMLDDDGDTTMSLHSQGSATTRHPEPRRTEHRAPSSTWRPVALTLLTLCLVLLIGLAALGLLFFQYYQLSNTGQDTISQMEERLGNTSQELQSLQVQNIKLAGSLQHVAEKLCRELYNKAGAHRCSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFFYSYWTGLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSPRSRDCVAILNGMIFSKDCKELKRCVCERRAGMVKPESLHVPPETLGEGD
Domain & Motif Annotations
Compositional Bias
18..30; Polar residues; 31..42; Basic and acidic residues
Domain (FT)
144..258; C-type lectin
Region
1..44; Disordered