Protein detail

CLC1A

C-type lectin domain family 1 member A (C-type lectin-like receptor 1) (CLEC-1)

Entry name
CLC1A
UniProt ID
EVMP confidence score
0.50
Supporting publications (n)
2
Transmembrane count
1
Protein classification
EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information8
Protein Names
C-type lectin domain family 1 member A (C-type lectin-like receptor 1) (CLEC-1)
Protein Function
Predicted intracellular proteins
Transmembrane
53..73; Helical; Signal-anchor for type II membrane protein
Transmembrane Count
1
Entrez Gene Symbol
Supporting publications (n)
2
EVMP confidence score
0.50
Fluorescence & Localization3
Tissue SpecificlungCell SpecificAlveolar cells type 1Single-Nuclei Brain Specificendothelial cell
Function & Pathway6
Relations & Evidence22

Ligand-Receptor Signaling (21)

21 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
transmembrane_tmhmmtransmembrane_predictedAlmen2009NoNoNoNoNo
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Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyMass spectrometryAntibody array9367978053976615839940641363985642898658527894104306466163208974339940641
Sequence, Structure & Domains6

Sequences

Length
280
Mass
31,952
Sequence
MQAKYSSTRDMLDDDGDTTMSLHSQGSATTRHPEPRRTEHRAPSSTWRPVALTLLTLCLVLLIGLAALGLLFFQYYQLSNTGQDTISQMEERLGNTSQELQSLQVQNIKLAGSLQHVAEKLCRELYNKAGAHRCSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFFYSYWTGLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSPRSRDCVAILNGMIFSKDCKELKRCVCERRAGMVKPESLHVPPETLGEGD

Domain & Motif Annotations

Compositional Bias
18..30; Polar residues; 31..42; Basic and acidic residues
Domain (FT)
144..258; C-type lectin
Region
1..44; Disordered
Supporting Publications2
PMIDTitleAbstract
37786918Rapid and in-depth proteomic profiling of small extracellular vesicles for ultralow samples.No abstract available
38321535Identification of specific markers for human pluripotent stem cell-derived small extracellular vesicles.No abstract available