Protein detail

CLC1A

C-type lectin domain family 1 member A (C-type lectin-like receptor 1) (CLEC-1)

Protein symbol
CLC1A
UniProt ID
EVMP score
0.50
Frequency
2
Transmembrane count
1
Protein classification
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
C-type lectin domain family 1 member A (C-type lectin-like receptor 1) (CLEC-1)
Protein Function
Predicted intracellular proteins
Transmembrane
53..73; Helical; Signal-anchor for type II membrane protein
Transmembrane Count
1
Entrez Gene Symbol
Frequency
2
EVMP Score
0.50
Fluorescence & Localization
Tissue SpecificlungCell SpecificAlveolar cells type 1Single-Nuclei Brain Specificendothelial cell
Function & Pathway
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

21 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
transmembrane_tmhmmtransmembrane_predictedAlmen2009NoNoNoNoNo
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Regulatory Interaction Network

0 records.

Protein Complex Composition

0 records.

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyMass spectrometryAntibody array9367978053976615839940641363985642898658527894104306466163208974339940641
Sequence, Structure & Domains

Sequences

Length
280
Mass
31,952
Sequence
MQAKYSSTRDMLDDDGDTTMSLHSQGSATTRHPEPRRTEHRAPSSTWRPVALTLLTLCLVLLIGLAALGLLFFQYYQLSNTGQDTISQMEERLGNTSQELQSLQVQNIKLAGSLQHVAEKLCRELYNKAGAHRCSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFFYSYWTGLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSPRSRDCVAILNGMIFSKDCKELKRCVCERRAGMVKPESLHVPPETLGEGD

3D Structural Models

Domain & Motif Annotations

Compositional Bias
18..30; Polar residues; 31..42; Basic and acidic residues
Domain (FT)
144..258; C-type lectin
Region
1..44; Disordered
Clinical Relevance