Protein detail
TMM52
Transmembrane protein 52
Entry name TMM52 | UniProt ID | EVMP confidence score 0.28 |
Supporting publications (n) 1 | Transmembrane count 1 | Protein classification |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Transmembrane protein 52
Protein Function
Predicted intracellular proteins
Transmembrane
56..76; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Supporting publications (n)
1
EVMP confidence score
0.28
Fluorescence & Localization
Cell SpecificLate spermatids
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Biological Process (3)
Mediation Categories
Other mediation
Relations & Evidence11
Ligand-Receptor Signaling (10)
10 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| transmembrane | transmembrane | UniProt_location | |||||
| transmembrane | transmembrane | UniProt_topology | |||||
| transmembrane | transmembrane | UniProt_keyword | |||||
| transmembrane_predicted | transmembrane | OmniPath | |||||
| transmembrane | transmembrane | Ramilowski_location | |||||
| transmembrane | transmembrane | OmniPath | |||||
| transmembrane | transmembrane_predicted | Phobius | |||||
| transmembrane_phobius | transmembrane_predicted | Almen2009 | |||||
| transmembrane_sosui | transmembrane_predicted | Almen2009 | |||||
| transmembrane_tmhmm | transmembrane_predicted | Almen2009 |
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion ChromatographyImmunoaffinity Capture | Mass spectrometryR Sequencing | 14 | 4098587937926756383966263017881134064677361468343811336835119778268265364018949730915084278218493820710638716512 |
Sequence, Structure & Domains
Sequences
Length
209
Mass
22,122
Sequence
MARGPLAARGLRLLLPLLPLLPLLPLPQVALGFADGSCDPSDQCPPQARWSSLWHVGLILLAVLLLLLCGVTAGCVRFCCLRKQAQAQPHLPPARQPCDVAVIPMDSDSPVHSTVTSYSSVQYPLGMRLPLPFGELDLDSMAPPAYSLYTPEPPPSYDEAVKMAKPREEGPALSQKPSPLLGASGLETTPVPQESGPNTQLPPCSPGAP
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8NDY8-1; Sequence=Displayed; Name=2; IsoId=Q8NDY8-2; Sequence=VSP_024420
Alternative Sequence
2..57; ARGPLAARGLRLLLPLLPLLPLLPLPQVALGFADGSCDPSDQCPPQARWSSLWHVG -> ERHCLLFILLTCLRWLCHDIPQGAGARWPRVSPVVEPCSPR (in isoform 2)
Domain & Motif Annotations
Compositional Bias
159..170; Basic and acidic residues; 186..202; Polar residues
Region
145..209; Disordered
Supporting Publications1
| PMID | Title | Related sentences |
|---|---|---|
| 36063136 | Liver-originated small extracellular vesicles with TM4SF5 target brown adipose tissue for homeostatic glucose clearance. | Liver-originated small extracellular vesicles with TM4SF5 target brown adipose tissue for homeostatic glucose clearance. |