Protein detail
PPTC7
Protein phosphatase PTC7 homolog (EC 3.1.3.16) (T-cell activation protein phosphatase 2C) (TA-PP2C) (T-cell activation protein phosphatase 2C-like)
Entry name PPTC7 | UniProt ID | EVMP score 0.38 |
Frequency 2 | Transmembrane count | Protein classification EnzymesPredicted intracellular proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Protein phosphatase PTC7 homolog (EC 3.1.3.16) (T-cell activation protein phosphatase 2C) (TA-PP2C) (T-cell activation protein phosphatase 2C-like)
Protein Class
EnzymesPredicted intracellular proteins
Protein Function
- Enzymes
- Predicted intracellular proteins
- ENZYME proteins:Hydrolases
Ensembl
Entrez Gene Symbol
Gene Synonym
TA-PP2C
Gene Description
Protein phosphatase targeting COQ7
Chromosome
12
Position
110533245-110583318
Frequency
2
EVMP Score
0.38
Fluorescence & Localization
Tissue SpecificepididymisCell SpecificAlveolar cells type 2Single-Nuclei Brain Specificdeep-layer corticothalamic and 6bBlood Cell Specificclassical monocyteBlood Lineage Specificdendritic cells
Function & Pathway
Protein Function
- Enzymes
- Predicted intracellular proteins
- ENZYME proteins:Hydrolases
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Metabolism mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
7 records.
| Component Name | Component Gene Symbols | Component UniProt ID | Stoichiometry | Database | Database IDs | References |
|---|---|---|---|---|---|---|
| PPTC7SEC14L2SEC14L4TRIB3UBC | O76054P0CG48Q8NI37Q96RU7Q9UDX3 | 1:1:1:1:1 | NetworkBlastCompleat | Compleat:HC5087 | ||
| PPTC7SEC14L2SEC14L4SLC2A8UBC | O76054P0CG48Q8NI37Q9NY64Q9UDX3 | 1:1:1:1:1 | NetworkBlastCompleat | Compleat:HC6073 | ||
| BLVRAPPTC7RRAGBRTN4IP1TRMT2B | P53004Q5VZM2Q8NI37Q8WWV3Q96GJ1 | 0:0:0:0:0 | hu.MAP2 | |||
| FMC1MOCS1OXLD1PPTC7TRMT2B | Q5BKU9Q8NI37Q96GJ1Q96HJ9Q9NZB8 | 0:0:0:0:0 | hu.MAP2 | |||
| PPTC7RTN4IP1 | Q8NI37Q8WWV3 | 0:0 | hu.MAP2 | |||
| FOXRED1PPTC7RTN4IP1 | Q8NI37Q8WWV3Q96CU9 | 0:0:0 | hu.MAP2 | |||
| FOXRED1PPTC7RTN4IP1TRMT2B | Q8NI37Q8WWV3Q96CU9Q96GJ1 | 0:0:0:0 | hu.MAP2 |
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion ChromatographyMicrofluidics-Based Methods | Mass spectrometry | 34 | 33718342364064913786238139949490315085003468166338225453398737264054596338644352327954143873186825950383268019192688484127723984282428433035349230550287306087003370951034202855273124283097589437686366384909582839651130760538313205914121688440311616400914553045137141315767 |
Sequence, Structure & Domains
Sequences
Length
304
Mass
32,646
Sequence
MFSVLSYGRLVARAVLGGLSQTDPRAGGGGGGDYGLVTAGCGFGKDFRKGLLKKGACYGDDACFVARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPIGILTTSYCELLQNKVPLLGSSTACIVVLDRTSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNSNYESIQQTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD
3D Structural Models
Domain & Motif Annotations
Domain (FT)
69..299; PPM-type phosphatase
Protein Families
PP2C family
Sequence Similarities
Belongs to the PP2C family.