Protein detail
ERMIN
Ermin (Juxtanodin) (JN)
Entry name ERMIN | UniProt ID | EVMP confidence score 0.53 |
Supporting publications (n) 1 | Transmembrane count | Protein classification Predicted intracellular proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Ermin (Juxtanodin) (JN)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym (3)
ERMINJNKIAA1189
Gene Description
Ermin
Chromosome
2
Position
157318631-157327713
Supporting publications (n)
1
EVMP confidence score
0.53
Fluorescence & Localization
Cell SpecificNeutrophils
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component (10)
Molecular Function (2)
Biological Process (3)
Mediation Categories
Fusion and delivery mediation
Relations & Evidence5
Ligand-Receptor Signaling (4)
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | |||||
| intracellular | intracellular | GO_Intercell | |||||
| intracellular | intracellular | UniProt_location | |||||
| intracellular | intracellular | OmniPath |
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation | R SequencingMass spectrometry | 1 | 27821849 |
Sequence, Structure & Domains
Sequences
Length
284
Mass
32,783
Sequence
MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8TAM6-1; Sequence=Displayed; Name=2; IsoId=Q8TAM6-2; Sequence=VSP_036982
Alternative Sequence
1; M -> MKTLSPDRIQPHIM (in isoform 2)
Domain & Motif Annotations
Compositional Bias
126..140; Basic and acidic residues; 171..183; Basic and acidic residues; 184..200; Acidic residues; 201..220; Basic and acidic residues; 225..235; Low complexity
Region
1..23; Disordered; 110..251; Disordered; 265..284; Binds actin
Supporting Publications1
| PMID | Title | Related sentences |
|---|---|---|
| 38780182 | LDHA-mediated M2-type macrophage polarization via tumor-derived exosomal EPHA2 promotes renal cell carcinoma progression. | Mechanistically, high expression of LDHA in ccRCC cells upregulated the expression of EPHA2 in exosomes derived from renal cancer. |