Protein detail
TM254
Transmembrane protein 254
Entry name TM254 | UniProt ID | EVMP confidence score 0.28 |
Supporting publications (n) 3 | Transmembrane count 3 | Protein classification Predicted membrane proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Transmembrane protein 254
Protein Class
Predicted membrane proteins
Transmembrane
15..35; Helical; 61..81; Helical; 95..115; Helical
Transmembrane Count
3
Ensembl
Entrez Gene Symbol
Gene Synonym (3)
bA369J21.6C10orf57FLJ13263
Gene Description
Transmembrane protein 254
Chromosome
10
Position
80078646-80092557
Supporting publications (n)
3
EVMP confidence score
0.28
Fluorescence & Localization
Cell SpecificEpididymal basal cellsSingle-Nuclei Brain Specificependymal cell
Function & Pathway
Cellular Component
Molecular Function
Biological Process (3)
Mediation Categories
Other mediation
Relations & Evidence9
Ligand-Receptor Signaling (8)
8 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | |||||
| intracellular | intracellular | OmniPath | |||||
| transmembrane | transmembrane | UniProt_location | |||||
| transmembrane | transmembrane | UniProt_topology | |||||
| transmembrane | transmembrane | UniProt_keyword | |||||
| transmembrane | transmembrane | Ramilowski_location | |||||
| transmembrane | transmembrane | OmniPath | |||||
| transmembrane | transmembrane_predicted | Phobius |
Sequence, Structure & Domains
Sequences
Length
123
Mass
14,243
Sequence
MATAAGATYFQRGSLFWFTVITLSFGYYTWVVFWPQSIPYQNLGPLGPFTQYLVDHHHTLLCNGYWLAWLIHVGESLYAIVLCKHKGITSGRAQLLWFLQTFFFGIASLTILIAYKRKRQKQT
Alternative Products
Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q8TBM7-1; Sequence=Displayed; Name=2; IsoId=Q8TBM7-2; Sequence=VSP_047062; Name=3; IsoId=Q8TBM7-3; Sequence=VSP_047063
Alternative Sequence
85..123; Missing (in isoform 2); 85..123; HKGITSGRAQLLWFLQTFFFGIASLTILIAYKRKRQKQT -> QNELRIRIKMRKLILRDSE (in isoform 3)
Supporting Publications3
| PMID | Title | Related sentences |
|---|---|---|
| 29603567 | Involvement of serum-derived exosomes of elderly patients with bone loss in failure of bone remodeling via alteration of exosomal bone-related proteins. | No related sentences available |
| 32384937 | Alzheimer's disease progression characterized by alterations in the molecular profiles and biogenesis of brain extracellular vesicles. | No related sentences available |
| 36028467 | Plasma exosomal DOK3 reflects immunological states in lung tumor and predicts prognosis of gefitinib treatment. | No related sentences available |