Protein detail
ZFP90
Zinc finger protein 90 homolog (Zfp-90) (Zinc finger protein 756)
Entry name ZFP90 | UniProt ID | EVMP score 0.38 |
Frequency 2 | Transmembrane count | Protein classification Predicted intracellular proteinsTranscription factors |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Zinc finger protein 90 homolog (Zfp-90) (Zinc finger protein 756)
Protein Class
Predicted intracellular proteinsTranscription factors
Protein Function
- Predicted intracellular proteins
- Transcription factors:Zinc-coordinating DNA-binding domains
Ensembl
Entrez Gene Symbol
Gene Synonym
KIAA1954NK10ZNF756
Gene Description
ZFP90 zinc finger protein
Chromosome
16
Position
68530090-68576072
Frequency
2
EVMP Score
0.38
Fluorescence & Localization
Tissue SpecificretinaCell SpecificAdipocytesSingle-Nuclei Brain SpecificleukocyteBlood Cell SpecificgdT-cellBlood Lineage SpecificNK-cells
Function & Pathway
Protein Function
- Predicted intracellular proteins
- Transcription factors:Zinc-coordinating DNA-binding domains
Cellular Component
Molecular Function
- GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
- GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
- GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
- GO:0005515 protein binding
- GO:0046872 metal ion binding
Biological Process
Canonical Pathways
- M5880 Naba ecm affiliated
- M5885 Naba matrisome associated
- M5889 Naba matrisome
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
Sequence, Structure & Domains
Sequences
Length
636
Mass
73,031
Sequence
MAPRPPTAAPQESVTFKDVSVDFTQEEWYHVDPAQRSLYRDVMLENYSHLVSLGYQVSKPEVIFKLEQGEEPWISEGEIQRPFYPDWKTRPEVKSSHLQQDVSEVSHCTHDLLHATLEDSWDVSSQLDRQQENWKRHLGSEASTQKKIITPQENFEQNKFGENSRLNTNLVTQLNIPARIRPSECETLGSNLGHNADLLNENNILAKKKPYKCDKCRKAFIHRSSLTKHEKTHKGEGAFPNGTDQGIYPGKKHHECTDCGKTFLWKTQLTEHQRIHTGEKPFECNVCGKAFRHSSSLGQHENAHTGEKPYQCSLCGKAFQRSSSLVQHQRIHTGEKPYRCNLCGRSFRHGTSLTQHEVTHSGEKPFQCKECGKAFSRCSSLVQHERTHTGEKPFECSICGRAFGQSPSLYKHMRIHKRGKPYQSSNYSIDFKHSTSLTQDESTLTEVKSYHCNDCGEDFSHITDFTDHQRIHTAENPYDCEQAFSQQAISHPGEKPYQCNVCGKAFKRSTSFIEHHRIHTGEKPYECNECGEAFSRRSSLTQHERTHTGEKPYECIDCGKAFSQSSSLIQHERTHTGEKPYECNECGRAFRKKTNLHDHQRIHTGEKPYSCKECGKNFSRSSALTKHQRIHTRNKL
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8TF47-1; Sequence=Displayed; Name=2; Synonyms=FOXP3-interacting KRAB-domain containing protein, FIK; IsoId=Q8TF47-3; Sequence=VSP_057516, VSP_057517
Alternative Sequence
86..113; DWKTRPEVKSSHLQQDVSEVSHCTHDLL -> GFVCLLPLSLPSGSKGERRQKLPRKNPE (in isoform 2); 114..636; Missing (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Zinc Finger
211..233; C2H2-type 1; 254..276; C2H2-type 2; 282..304; C2H2-type 3; 310..332; C2H2-type 4; 338..360; C2H2-type 5; 366..388; C2H2-type 6; 394..416; C2H2-type 7; 450..472; C2H2-type 8; 497..519; C2H2-type 9; 525..547; C2H2-type 10; 553..575; C2H2-type 11; 581..603; C2H2-type 12; 609..631; C2H2-type 13
Domain (FT)
14..85; KRAB
Protein Families
Krueppel C2H2-type zinc-finger protein family
Sequence Similarities
Belongs to the krueppel C2H2-type zinc-finger protein family.
Clinical Relevance
Antibody
Interaction Protein
ENSG00000130726
Interaction Count
1
Interaction Dataset
biogrid_opencell_bioplex