Protein detail
S35F5
Solute carrier family 35 member F5 (Hepatitis C virus NS5A-transactivated protein 3) (HCV NS5A-transactivated protein 3)
Entry name S35F5 | UniProt ID | EVMP confidence score 0.40 |
Supporting publications (n) 1 | Transmembrane count 10 | Protein classification Predicted membrane proteinsTransporters |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Solute carrier family 35 member F5 (Hepatitis C virus NS5A-transactivated protein 3) (HCV NS5A-transactivated protein 3)
Protein Class (2)
Predicted membrane proteinsTransporters
Protein Function
Transporters:Electrochemical Potential-driven transporters
Transmembrane
69..89; Helical; 101..121; Helical; 243..263; Helical; 268..288; Helical; 296..316; Helical; 327..347; Helical; 361..381; Helical; 395..415; Helical; 420..440; Helical; 452..472; Helical
Transmembrane Count
10
Ensembl
Entrez Gene Symbol
Gene Synonym
FLJ22004
Gene Description
Solute carrier family 35 member F5
Chromosome
2
Position
113705011-113756693
Supporting publications (n)
1
EVMP confidence score
0.40
Fluorescence & Localization
Tissue SpecificbrainCell SpecificBrain excitatory neuronsBlood Lineage SpecificB-cells
Function & Pathway
Protein Function
Transporters:Electrochemical Potential-driven transporters
Cellular Component
Biological Process (3)
Mediation Categories
Other mediation
Relations & Evidence9
Ligand-Receptor Signaling (8)
8 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| receptor | receptor | OmniPath | Yes | ||||
| transmembrane | transmembrane | UniProt_location | |||||
| transmembrane | transmembrane | UniProt_topology | |||||
| transmembrane | transmembrane | UniProt_keyword | |||||
| transmembrane | transmembrane | Ramilowski_location | |||||
| transmembrane | transmembrane | OmniPath | |||||
| receptor | receptor | scConnect | Yes | ||||
| transmembrane | transmembrane_predicted | Phobius |
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Size Exclusion Chromatography | ELISA | 1 | 39702169 |
Sequence, Structure & Domains
Sequences
Length
523
Mass
58,887
Sequence
MVPPRRHRGAGRPGVLSSSPPFRLRSAKFSGIALEDLRRALKTRLQMVCVFVMNRMNSQNSGFTQRRRMALGIVILLLVDVIWVASSELTSYVFTQYNKPFFSTFAKTSMFVLYLLGFIIWKPWRQQCTRGLRGKHAAFFADAEGYFAACTTDTTMNSSLSEPLYVPVKFHDLPSEKPESTNIDTEKTPKKSRVRFSNIMEIRQLPSSHALEAKLSRMSYPVKEQESILKTVGKLTATQVAKISFFFCFVWFLANLSYQEALSDTQVAIVNILSSTSGLFTLILAAVFPSNSGDRFTLSKLLAVILSIGGVVLVNLAGSEKPAGRDTVGSIWSLAGAMLYAVYIVMIKRKVDREDKLDIPMFFGFVGLFNLLLLWPGFFLLHYTGFEDFEFPNKVVLMCIIINGLIGTVLSEFLWLWGCFLTSSLIGTLALSLTIPLSIIADMCMQKVQFSWLFFAGAIPVFFSFFIVTLLCHYNNWDPVMVGIRRIFAFICRKHRIQRVPEDSEQCESLISMHSVSQEDGAS
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8WV83-1; Sequence=Displayed; Name=2; IsoId=Q8WV83-2; Sequence=VSP_029665, VSP_029666, VSP_029667, VSP_029668
Alternative Sequence
1..6; Missing (in isoform 2); 7..13; HRGAGRP -> MDSSGWR (in isoform 2); 248..250; CFV -> ALW (in isoform 2); 251..523; Missing (in isoform 2)
Domain & Motif Annotations
Domain (FT)
252..316; EamA
Protein Families
SLC35F solute transporter family
Sequence Similarities
Belongs to the SLC35F solute transporter family.
Supporting Publications1
| PMID | Title | Related sentences |
|---|---|---|
| 24700864 | Human urinary exosomes as innate immune effectors. | No related sentences available |