Protein detail
DNJA4
DnaJ homolog subfamily A member 4
Entry name DNJA4 | UniProt ID | EVMP confidence score 0.53 |
Supporting publications (n) 5 | Transmembrane count | Protein classification Predicted intracellular proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
DnaJ homolog subfamily A member 4
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
PRO1472
Gene Description
DnaJ heat shock protein family (Hsp40) member A4
Chromosome
15
Position
78264086-78282196
Supporting publications (n)
5
EVMP confidence score
0.53
Fluorescence & Localization
Cell SpecificAdipocytesSingle-Nuclei Brain Specificfibroblast
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component (3)
Molecular Function (6)
Reactome (2)
Mediation Categories
Receptor-signaling mediation
Relations & Evidence5
Ligand-Receptor Signaling (3)
3 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | |||||
| intracellular | intracellular | GO_Intercell | |||||
| intracellular | intracellular | OmniPath |
Protein Complex Composition (2)
2 records.
| Component Name | Component Gene Symbols | Component UniProt ID | Stoichiometry | Database | Database IDs | References |
|---|---|---|---|---|---|---|
| HT_SC_Cluster72 | CPVLCTSADNAJA1DNAJA3DNAJA4DNAJB14DNAJC3DNAJC7HSPA5IDH1IDH2 | O75874P10619P11021P31689P48735Q13217Q8TBM8Q8WW22Q96EY1Q99615Q9H3G5 | 1:1:1:1:1:1:1:1:1:1:1 | Compleat | Compleat:HC2279 | |
| BAZ1ADNAJA4H2AXHSPA1BLIG3MRE11RAD50SUMO2TCF7L2TERF2IPXRCC5XRCC6 | P0DMV9P12956P13010P16104P49916P49959P61956Q8WW22Q92878Q9NQB0Q9NRL2Q9NYB0 | 1:1:1:1:1:1:1:1:1:1:1:1 | NetworkBlastCompleat | Compleat:HC5822 |
Sequence, Structure & Domains
Sequences
Length
397
Mass
44,798
Sequence
MVKETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEGEKFKLISQAYEVLSDPKKRDVYDQGGEQAIKEGGSGSPSFSSPMDIFDMFFGGGGRMARERRGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKGSVEKCPLCKGRGMQIHIQQIGPGMVQQIQTVCIECKGQGERINPKDRCESCSGAKVIREKKIIEVHVEKGMKDGQKILFHGEGDQEPELEPGDVIIVLDQKDHSVFQRRGHDLIMKMKIQLSEALCGFKKTIKTLDNRILVITSKAGEVIKHGDLRCVRDEGMPIYKAPLEKGILIIQFLVIFPEKHWLSLEKLPQLEALLPPRQKVRITDDMDQVELKEFCPNEQNWRQHREAYEEDEDGPQAGVQCQTA
Alternative Products
Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q8WW22-1; Sequence=Displayed; Name=2; IsoId=Q8WW22-2; Sequence=VSP_038965; Name=3; IsoId=Q8WW22-3; Sequence=VSP_045696
Alternative Sequence
1..44; MVKETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEGEK -> MWESLTLDSGQISALTR (in isoform 3); 1; M -> MARGGSQSWSSGESDGQPKEQTPEKPRHKM (in isoform 2)
Domain & Motif Annotations
Repeat
135..142; CXXCXGXG motif; 151..158; CXXCXGXG motif; 178..185; CXXCXGXG motif; 194..201; CXXCXGXG motif
Zinc Finger
122..206; CR-type
Domain (FT)
4..70; J
Clinical Relevance
Supporting Publications5
| PMID | Title | Related sentences |
|---|---|---|
| 33709510 | Unbiased proteomic profiling of host cell extracellular vesicle composition and dynamics upon HIV-1 infection. | No related sentences available |
| 37922300 | Proteomic profiling of urinary extracellular vesicles differentiates breast cancer patients from healthy women. | No related sentences available |
| 38225453 | Deep proteomic analysis of obstetric antiphospholipid syndrome by DIA-MS of extracellular vesicle enriched fractions. | No related sentences available |
| 40091455 | Potential Role of Menstrual Fluid-Derived Small Extracellular Vesicle Proteins in Endometriosis Pathogenesiss. | No related sentences available |
| 40098346 | Toward Identification of Markers for Brain-Derived Extracellular Vesicles in Cerebrospinal Fluid: A Large-Scale, Unbiased Analysis Using Proximity Extension Assays. | No related sentences available |