Protein detail

CA054

Uncharacterized protein C1orf54

Entry name CA054	UniProt ID Q8WWF1	EVMP confidence score 0.38
Supporting publications (n) 1	Transmembrane count	Protein classification Predicted secreted proteins

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40

Basic Information11

Protein Names

Uncharacterized protein C1orf54

Protein Class

Predicted secreted proteins

Protein Function

Predicted secreted proteins

Ensembl

ENSG00000118292

Entrez Gene Symbol

C1orf54

Gene Synonym

FLJ23221

Gene Description

Chromosome 1 open reading frame 54

Chromosome

Position

150268200-150280916

Supporting publications (n)

EVMP confidence score

0.38

Fluorescence & Localization7

Tissue Specificadipose tissueCell SpecificAdipocytesSingle-Nuclei Brain Specifichippocampal dentate gyrusBlood Cell Specificplasmacytoid DCBlood Lineage Specificdendritic cellsSecretome LocationIntracellular and membraneSecretome FunctionReceptor

Function & Pathway4

Protein Function

Predicted secreted proteins

Cellular Component

GO:0005576 extracellular region

Biological Process (3)

Mediation Categories

Other mediation

Relations & Evidence9

Ligand-Receptor Signaling (8)

8 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
ecm	ecm	MatrixDB	Yes	No	Yes	No	No
ecm	ecm	OmniPath	Yes	No	Yes	No	No
intracellular	intracellular	GO_Intercell	No	No	Yes	No	No
intracellular	intracellular	OmniPath	No	No	Yes	No	No
secreted	secreted	UniProt_keyword	No	No	Yes	No	No
secreted	secreted	UniProt_location	No	No	Yes	No	No
secreted	secreted	HPA_secretome	No	No	Yes	No	No
secreted	secreted	OmniPath	No	No	Yes	No	No

Isolation & Detection Technology (1)

1 record.

EV Isolation Method	Detection Method	Number of References	References
Differential UltracentrifugationSize Exclusion ChromatographyPolymer PrecipitationImmunoaffinity Capture	Mass spectrometry	15	40985879 38207106 38113368 40465195 37322475 35359923 32854315 40940449 41307968 40840701 32230970 34576246 37204515 39207047 30646616

Sequence, Structure & Domains3

Sequences

Length

131

Mass

14,923

Sequence

MDVLFVAIFAVPLILGQEYEDEERLGEDEYYQVVYYYTVTPSYDDFSADFTIDYSIFESEDRLNRLDKDITEAIETTISLETARADHPKPVTVKPVTTEPSPDLNDAVSSLRSPIPLLLSCAFVQVGMYFM

Clinical Relevance1

Antibody (2)

HPA026518 HPA043874

Supporting Publications1

PMID	Title	Abstract
40098346	Toward Identification of Markers for Brain-Derived Extracellular Vesicles in Cerebrospinal Fluid: A Large-Scale, Unbiased Analysis Using Proximity Extension Assays.	No abstract available