Protein detail

SUSD6

Sushi domain-containing protein 6 (Drug-activated gene overexpressed protein)

Entry name
SUSD6
UniProt ID
EVMP confidence score
0.28
Supporting publications (n)
5
Transmembrane count
1
Protein classification
Predicted membrane proteins
Basic Information
Protein Names
Sushi domain-containing protein 6 (Drug-activated gene overexpressed protein)
Protein Class
Predicted membrane proteins
Transmembrane
121..141; Helical
Transmembrane Count
1
Entrez Gene Symbol
Gene Synonym
KIAA0247
Gene Description
Sushi domain containing 6
Chromosome
14
Position
69611596-69715144
Supporting publications (n)
5
EVMP confidence score
0.28
Fluorescence & Localization
SUSD6 fluorescence
Cell SpecificBreast lactating cells
Function & Pathway
Relations & Evidence14

Ligand-Receptor Signaling (13)

13 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
cell_surfacecell_surfaceSurfaceomeYes
cell_surfacecell_surfaceOmniPathYes
transmembranetransmembrane_predictedPhobiusYes
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Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationMass spectrometryELISA23391918340311616
Sequence, Structure & Domains

Sequences

Length
303
Mass
32,090
Sequence
MCHGRIAPKSTSVFAVASVGHGVFLPLVILCTLLGDGLASVCPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEISCRLNEDKDTHTSLGVPTLSIVASTASSVALILLLVVLFVLLQPKLKSFHHSRRDQGVSGDQVSIMVDGVQVALPSYEEAVYGSSGHCVPPADPRVQIVLSEGSGPSGRSVPREQQLPDQGACSSAGGEDEAPGQSGLCEAWGSRASETVMVHQATTSSWVAGSGNRQLAHKETADSENSDIQSLLSLTSEEYTDDIPLLKEA

Domain & Motif Annotations

Domain (FT)
40..104; Sushi
Region
199..237; Disordered; 263..282; Disordered
Clinical Relevance
Disease Involvement
Tumor suppressor
Antibody (2)
Supporting Publications5
PMIDTitleRelated sentences
30550287Label-Free Proteomic Analysis of Exosomes Secreted from THP-1-Derived Macrophages Treated with IFN-α Identifies Antiviral Proteins Enriched in Exosomes.No related sentences available
30805606Ionizing radiation affects the composition of the proteome of extracellular vesicles released by head-and-neck cancer cells in vitro.No related sentences available
38731868The Deep Proteomics Approach Identified Extracellular Vesicular Proteins Correlated to Extracellular Matrix in Type One and Two Endometrial Cancer.No related sentences available
39290459Urinary extracellular vesicles as a monitoring tool for renal damage in patients not meeting criteria for chronic kidney disease.No related sentences available
40098346Toward Identification of Markers for Brain-Derived Extracellular Vesicles in Cerebrospinal Fluid: A Large-Scale, Unbiased Analysis Using Proximity Extension Assays.No related sentences available