Protein detail

TTC17

Tetratricopeptide repeat protein 17 (TPR repeat protein 17)

Entry name
TTC17
UniProt ID
Q96AE7
EVMP confidence score
0.28
Supporting publications (n)
1
Transmembrane count
Protein classification
Predicted intracellular proteins
Basic Information
Protein Names
Tetratricopeptide repeat protein 17 (TPR repeat protein 17)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
ENSG00000052841
Entrez Gene Symbol
TTC17
Gene Synonym
FLJ10890
Gene Description
Tetratricopeptide repeat domain 17
Chromosome
11
Position
43358920-43494933
Supporting publications (n)
1
EVMP confidence score
0.28
Fluorescence & Localization
TTC17 fluorescence
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component (4)
Molecular Function
GO:0005515 protein binding
Biological Process (3)
Mediation Categories
Fusion and delivery mediation
Relations & Evidence9

Ligand-Receptor Signaling (6)

6 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPI
intracellularintracellularGO_Intercell
intracellularintracellularUniProt_location
intracellularintracellularOmniPath
plasma_membraneplasma_membraneUniProt_location
plasma_membraneplasma_membraneOmniPath

Protein Complex Composition (2)

2 records.

Component NameComponent Gene SymbolsComponent UniProt IDStoichiometryDatabaseDatabase IDsReferences
BMPR1BMRPL44SMAD6SMAD7SMURF1TTC17O00238O15105O43541Q96AE7Q9H9J2Q9HCE71:1:1:1:1:1NetworkBlastCompleatCompleat:HC8435
ATF6TMEM131TTC17P18850Q92545Q96AE70:0:0hu.MAP

Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationDensity Gradient CentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion ChromatographyMass spectrometryMass spectrometry [QTOF]Western blotting1334186243276054332786353732284825330358143816890639409015289865852789410428590090296876283064661632089743
Sequence, Structure & Domains

Sequences

Length
1,141
Mass
129,558
Sequence
MAAAVGVRGRYELPPCSGPGWLLSLSALLSVAARGAFATTHWVVTEDGKIQQQVDSPMNLKHPHDLVILMRQEATVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVPLGDLDLYDGTYITLESKDISPEDYIDTESPVPPDPEQPDCTKILELPYSIHAFQHLRGVQERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGLQKNTSSWVLYNMASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAALDDSDFFTSYYTLGNIYAMLGEYNHSVLCYDHALQARPGFEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKLIQEEQILRNIIHETQMAKEAQLGNHQICRLVNQQHSLHCQWDQPVRYHRGDIFENVDYVQFGEDSSTSSMMSVNFDVQSNQSDINDSVKSSPVAHSILWIWGRDSDAYRDKQHILWPKRADCTESYPRVPVGGELPTYFLPPENKGLRIHELSSDDYSTEEEAQTPDCSITDFRKSHTLSYLVKELEVRMDLKAKMPDDHARKILLSRINNYTIPEEEIGSFLFHAINKPNAPIWLILNEAGLYWRAVGNSTFAIACLQRALNLAPLQYQDVPLVNLANLLIHYGLHLDATKLLLQALAINSSEPLTFLSLGNAYLALKNISGALEAFRQALKLTTKCPECENSLKLIRCMQFYPFLYNITSSVCSGTVVEESNGSDEMENSDETKMSEEILALVDEFQQAWPLEGFGGALEMKGRRLDLQGIRVLKKGPQDGVARSSCYGDCRSEDDEATEWITFQVKRVKKPKGDHKKTPGKKVETGQIENGHRYQANLEITGPKVASPGPQGKKRDYQRLGWPSPDECLKLRWVELTAIVSTWLAVSSKNIDITEHIDFATPIQQPAMEPLCNGNLPTSMHTLDHLHGVSNRASLHYTGESQLTEVLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKGRRSP
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q96AE7-1; Sequence=Displayed; Name=2; IsoId=Q96AE7-2; Sequence=VSP_056857, VSP_056858, VSP_056859
Alternative Sequence
751; G -> GNCHEKTLDNSHDKQKYFDNSQSLDAAEEEPSERGTEEDPVFSVENSGRDSDALRLES (in isoform 2); 890..898; KKRDYQRLG -> LLDWKTRKV (in isoform 2); 899..1140; Missing (in isoform 2)

Domain & Motif Annotations

Repeat
295..328; TPR 1; 619..652; TPR 2; 689..722; TPR 3; 1014..1048; TPR 4; 1051..1084; TPR 5; 1085..1118; TPR 6
Coiled Coil
340..382
Protein Families
TTC17 family
Sequence Similarities
Belongs to the TTC17 family.
Clinical Relevance
Antibody
HPA038508
Supporting Publications1
PMIDTitleRelated sentences
39996590Surface Double Dendritic Magnetic Microfibrils for Rapid Isolation and Proteomic Profiling of Extracellular Vesicles from Microliters of Biofluids.No related sentences available