Protein detail

LENG1

Leukocyte receptor cluster member 1

Entry name LENG1	UniProt ID Q96BZ8	EVMP score 0.38
Frequency 3	Transmembrane count	Protein classification Essential proteinsPredicted intracellular proteins

EVMP score: annotation confidence score.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40

Basic Information

Protein Names

Leukocyte receptor cluster member 1

Protein Class

Essential proteinsPredicted intracellular proteins

Protein Function

Predicted intracellular proteins

Ensembl

ENSG00000105617

Entrez Gene Symbol

LENG1

Gene Description

Leukocyte receptor cluster member 1

Chromosome

Position

54155161-54159721

Frequency

EVMP Score

0.38

Fluorescence & Localization

Tissue SpecificepididymisCell SpecificCytotrophoblastsSingle-Nuclei Brain Specificfibroblast

Function & Pathway

Protein Function

Predicted intracellular proteins

Cellular Component

Molecular Function

Biological Process

Reactome

Mediation Categories

Other mediation

Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

3 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
intracellular	intracellular	ComPPI	No	No	No	No	No
intracellular	intracellular	GO_Intercell	No	No	No	No	No
intracellular	intracellular	OmniPath	No	No	No	No	No

Regulatory Interaction Network

0 records.

Protein Complex Composition

5 records.

Component Gene Symbols	Component UniProt ID	Stoichiometry	Database
CDC40 LENG1 NCBP1 NCBP2 PHAX	O60508 P52298 Q09161 Q96BZ8 Q9H814	0:0:0:0:0	hu.MAP2
LENG1 NCBP1 NCBP2 PHAX SRRT	P52298 Q09161 Q96BZ8 Q9BXP5 Q9H814	0:0:0:0:0	hu.MAP2
LENG1 NCBP1 NCBP2 PHAX	P52298 Q09161 Q96BZ8 Q9H814	0:0:0:0	hu.MAP2
LENG1 NCBP2 USP45	P52298 Q70EL2 Q96BZ8	0:0:0	hu.MAP
LENG1 NCBP2	P52298 Q96BZ8	0:0	hu.MAP

Isolation & Detection Technology

1 record.

EV Isolation Method	Detection Method	Number of References	References
Differential UltracentrifugationSize Exclusion Chromatography	Mass spectrometry	2	36982991 38922971

Sequence, Structure & Domains

Sequences

Length

264

Mass

30,528

Sequence

MNILPKKSWHVRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFRELLEEGKGVIRGNKEYKEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLARRPRQQDPHLTH

3D Structural Models

Domain & Motif Annotations

Compositional Bias

12..37; Basic and acidic residues; 59..75; Low complexity; 146..162; Basic and acidic residues; 170..214; Basic and acidic residues

Coiled Coil

16..46; 89..115; 196..222

Region

1..37; Disordered; 49..76; Disordered; 118..264; Disordered

Clinical Relevance

Antibody

HPA043541

Interaction Protein

ENSG00000019995ENSG00000094796ENSG00000100109

Interaction Count

Interaction Dataset

intact_biogrid