Protein detail
STAR4
StAR-related lipid transfer protein 4 (START domain-containing protein 4) (StARD4)
Entry name STAR4 | UniProt ID | EVMP confidence score 0.28 |
Supporting publications (n) 3 | Transmembrane count | Protein classification Metabolic proteinsPredicted intracellular proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
StAR-related lipid transfer protein 4 (START domain-containing protein 4) (StARD4)
Protein Class (2)
Metabolic proteinsPredicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Description
StAR related lipid transfer domain containing 4
Chromosome
5
Position
111496033-111512590
Supporting publications (n)
3
EVMP confidence score
0.28
Fluorescence & Localization
Cell SpecificLate spermatids
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component (4)
Molecular Function (3)
Biological Process (3)
Reactome (4)
Mediation Categories (2)
Fusion and delivery mediationMetabolism mediation
Relations & Evidence5
Ligand-Receptor Signaling (3)
3 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | |||||
| intracellular | intracellular | GO_Intercell | |||||
| intracellular | intracellular | OmniPath |
Protein Complex Composition (1)
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Size Exclusion Chromatography | Mass spectrometry | 1 | 38343172 |
Sequence, Structure & Domains
Sequences
Length
205
Mass
23,517
Sequence
MEGLSDVASFATKLKNTLIQYHSIEEDKWRVAKKTKDVTVWRKPSEEFNGYLYKAQGVIDDLVYSIIDHIRPGPCRLDWDSLMTSLDILENFEENCCVMRYTTAGQLWNIISPREFVDFSYTVGYKEGLLSCGISLDWDEKRPEFVRGYNHPCGWFCVPLKDNPNQSLLTGYIQTDLRGMIPQSAVDTAMASTLTNFYGDLRKAL
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q96DR4-1; Sequence=Displayed; Name=2; IsoId=Q96DR4-2; Sequence=VSP_057170
Alternative Sequence
134..204; ISLDWDEKRPEFVRGYNHPCGWFCVPLKDNPNQSLLTGYIQTDLRGMIPQSAVDTAMASTLTNFYGDLRKA -> NNLNMLCFFSVWFKYLCFLGWMSLS (in isoform 2)
3D Structural Models
Turn
107..110
Helix
7..22; 26..28; 63..70; 74..79; 183..204
Beta Strand
30..34; 36..44; 46..61; 71..73; 83..93; 96..103; 114..125; 128..135; 145..147; 152..160; 163..173
3D Structure
X-ray crystallography (2)
Domain & Motif Annotations
Domain (FT)
1..205; START
Supporting Publications3
| PMID | Title | Related sentences |
|---|---|---|
| 37322475 | Comprehensive profiling of extracellular vesicles in uveitis and scleritis enables biomarker discovery and mechanism exploration. | No related sentences available |
| 38207106 | Proteomic, Metabolomic, and Fatty Acid Profiling of Small Extracellular Vesicles from Glioblastoma Stem-Like Cells and Their Role in Tumor Heterogeneity. | No related sentences available |
| 40985879 | TurboID-Mediated Profiling of Glioblastoma-Derived Extracellular Vesicle Cargo Proteins. | No related sentences available |