Protein detail

CK024

Uncharacterized protein C11orf24 (Protein DM4E3)

Entry name
CK024
UniProt ID
EVMP confidence score
0.25
Supporting publications (n)
1
Transmembrane count
1
Protein classification
Predicted intracellular proteinsPredicted membrane proteins
EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information13
Protein Names
Uncharacterized protein C11orf24 (Protein DM4E3)
Protein Class (2)
Predicted intracellular proteinsPredicted membrane proteins
Protein Function
Predicted intracellular proteins
Transmembrane
401..421; Helical
Transmembrane Count
1
Entrez Gene Symbol
Gene Synonym
DM4E3
Gene Description
Chromosome 11 open reading frame 24
Chromosome
11
Position
68261338-68272001
Supporting publications (n)
1
EVMP confidence score
0.25
Fluorescence & Localization1
Cell SpecificCardiomyocytes
Function & Pathway5
Relations & Evidence24

Ligand-Receptor Signaling (21)

21 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
transmembrane_tmhmmtransmembrane_predictedAlmen2009NoNoNoYesNo
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Protein Complex Composition (2)

2 records.

Component NameComponent Gene SymbolsComponent UniProt IDStoichiometryDatabaseDatabase IDsReferences
C11orf24CCDC186PIBF1TSNAXIP1VAT1LQ2TAA8Q7Z3E2Q8WXW3Q96F05Q9HCJ60:0:0:0:0hu.MAP2
C11orf24VAT1LQ96F05Q9HCJ60:0hu.MAP2

Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyFACSMass spectrometry137022097
Sequence, Structure & Domains5

Sequences

Length
449
Mass
46,101
Sequence
MWTALVLIWIFSLSLSESHAASNDPRNFVPNKMWKGLVKRNASVETVDNKTSEDVTMAAASPVTLTKGTSAAHLNSMEVTTEDTSRTDVSEPATSGGAADGVTSIAPTAVASSTTAASITTAASSMTVASSAPTTAASSTTVASIAPTTAASSMTAASSTPMTLALPAPTSTSTGRTPSTTATGHPSLSTALAQVPKSSALPRTATLATLATRAQTVATTANTSSPMSTRPSPSKHMPSDTAASPVPPMRPQAQGPISQVSVDQPVVNTTNKSTPMPSNTTPEPAPTPTVVTTTKAQAREPTASPVPVPHTSPIPEMEAMSPTTQPSPMPYTQRAAGPGTSQAPEQVETEATPGTDSTGPTPRSSGGTKMPATDSCQPSTQGQYMVVTTEPLTQAVVDKTLLLVVLLLGVTLFITVLVLFALQAYESYKKKDYTQVDYLINGMYADSEM

Domain & Motif Annotations

Compositional Bias
154..184; Low complexity; 215..234; Low complexity; 255..279; Polar residues; 352..367; Polar residues
Region
72..101; Disordered; 154..187; Disordered; 215..381; Disordered
Clinical Relevance1
Supporting Publications1
PMIDTitleAbstract
31852509A comprehensive proteomics profiling identifies NRP1 as a novel identity marker of human bone marrow mesenchymal stromal cell-derived small extracellular vesicles.No abstract available