Protein detail

ZN503

Zinc finger protein 503

Protein symbol ZN503	UniProt ID Q96F45	EVMP score 0.38
Frequency 1	Transmembrane count	Protein classification Predicted intracellular proteins

Basic Information

Protein Names

Zinc finger protein 503

Protein Class

Predicted intracellular proteins

Protein Function

Predicted intracellular proteins

Ensembl

ENSG00000165655

Entrez Gene Symbol

ZNF503

Gene Synonym

FLJ45745MGC2555Nlz2

Gene Description

Zinc finger protein 503

Chromosome

Position

75397830-75401764

Frequency

EVMP Score

0.38

Fluorescence & Localization

Function & Pathway

Protein Function

Predicted intracellular proteins

Cellular Component

GO:0005634 nucleus

Molecular Function

Biological Process

Mediation Categories

Other mediation

Relations & Evidence

Enzyme-Mediated Modification

1 record.

Substrate Gene Symbol	Enzyme Gene Symbol	Enzyme UniProt ID	Residue Type	Residue Offset	Modification	Database	References
ZNF503	EGF	P01133	S	98	phosphorylation	BEL-Large-Corpus_ProtMapperProtMapper	ProtMapper:17081983

Ligand-Receptor Signaling

4 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
intracellular	intracellular	ComPPI	No	No	No	No	No
intracellular	intracellular	GO_Intercell	No	No	No	No	No
intracellular	intracellular	UniProt_location	No	No	No	No	No
intracellular	intracellular	OmniPath	No	No	No	No	No

Regulatory Interaction Network

1 record.

Source Protein Symbol	Source UniProt ID	Target Protein Symbol	Target UniProt ID	Is Directed	Is Stimulation	Is Inhibition	Database	References
TLE5	Q08117	ZN503	Q96F45	Yes	No	Yes	HuRISIGNOR	SIGNOR:19056829

Protein Complex Composition

1 record.

Component Name	Component Gene Symbols	Component UniProt ID	Stoichiometry	Database	Database IDs	References
	HADHB TIMM13 TIMM8B ZNF503	P55084 Q96F45 Q9Y5J9 Q9Y5L4	1:1:1:1	NetworkBlastCompleat	Compleat:HC8970

Isolation & Detection Technology

1 record.

EV Isolation Method	Detection Method	Number of References	References
Differential UltracentrifugationSize Exclusion Chromatography	Mass spectrometry	4	37322475 41068253 36146834 40831280

Sequence, Structure & Domains

Sequences

Length

646

Mass

62,555

Sequence

MSTAPSLSALRSSKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPSPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPSVMTASLCRDPYCLSYHCASHLAGAAAASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHSSLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHICNWVSANGPCDKRFATSEELLSHLRTHTAFPGTDKLLSGYPSSSSLASAAAAAMACHMHIPTSGAPGSPGTLALRSPHHALGLSSRYHPYSKSPLPTPGAPVPVPAATGPYYSPYALYGQRLTTASALGYQ

Alternative Products

Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q96F45-1; Sequence=Displayed; Name=2; IsoId=Q96F45-2; Sequence=VSP_026395; Name=3; IsoId=Q96F45-3; Sequence=VSP_026394

Alternative Sequence

130..492; Missing (in isoform 3); 233..269; Missing (in isoform 2)

3D Structural Models

Domain & Motif Annotations

Compositional Bias

1..11; Polar residues; 16..28; Gly residues; 34..52; Low complexity; 130..139; Low complexity; 140..152; Gly residues; 189..205; Gly residues; 217..226; Polar residues; 227..240; Low complexity; 250..259; Basic and acidic residues; 260..277; Gly residues; 300..315; Gly residues; 316..330; Low complexity

Zinc Finger

514..542; C2H2-type

Region

1..70; Disordered; 121..332; Disordered

Protein Families

Elbow/Noc family

Sequence Similarities

Belongs to the Elbow/Noc family.

Clinical Relevance

Antibody

HPA026848

Interaction Protein

ENSG00000136485

Interaction Count

Interaction Dataset

biogrid_bioplex