Protein detail
ZN503
Zinc finger protein 503
Entry name ZN503 | UniProt ID | EVMP confidence score 0.38 |
Supporting publications (n) 1 | Transmembrane count | Protein classification Predicted intracellular proteins |
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40Basic Information11
Protein Names
Zinc finger protein 503
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym (3)
FLJ45745MGC2555Nlz2
Gene Description
Zinc finger protein 503
Chromosome
10
Position
75397830-75401764
Supporting publications (n)
1
EVMP confidence score
0.38
Function & Pathway5
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function (2)
Biological Process (3)
Mediation Categories
Other mediation
Relations & Evidence8
Enzyme-Mediated Modification (1)
1 record.
| Substrate Gene Symbol | Enzyme Gene Symbol | Enzyme UniProt ID | Residue Type | Residue Offset | Modification | Database | References |
|---|---|---|---|---|---|---|---|
| ZNF503 | EGF | P01133 | S | 98 | phosphorylation | BEL-Large-Corpus_ProtMapperProtMapper | ProtMapper:17081983 |
Ligand-Receptor Signaling (4)
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Regulatory Interaction Network (1)
1 record.
| Source Protein Symbol | Source UniProt ID | Target Protein Symbol | Target UniProt ID | Is Directed | Is Stimulation | Is Inhibition | Database | References |
|---|---|---|---|---|---|---|---|---|
| TLE5 | Q08117 | ZN503 | Q96F45 | Yes | No | Yes | HuRISIGNOR | SIGNOR:19056829 |
Protein Complex Composition (1)
Sequence, Structure & Domains10
Sequences
Length
646
Mass
62,555
Sequence
MSTAPSLSALRSSKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPSPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPSVMTASLCRDPYCLSYHCASHLAGAAAASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHSSLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHICNWVSANGPCDKRFATSEELLSHLRTHTAFPGTDKLLSGYPSSSSLASAAAAAMACHMHIPTSGAPGSPGTLALRSPHHALGLSSRYHPYSKSPLPTPGAPVPVPAATGPYYSPYALYGQRLTTASALGYQ
Alternative Products
Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q96F45-1; Sequence=Displayed; Name=2; IsoId=Q96F45-2; Sequence=VSP_026395; Name=3; IsoId=Q96F45-3; Sequence=VSP_026394
Alternative Sequence
130..492; Missing (in isoform 3); 233..269; Missing (in isoform 2)
Domain & Motif Annotations
Compositional Bias
1..11; Polar residues; 16..28; Gly residues; 34..52; Low complexity; 130..139; Low complexity; 140..152; Gly residues; 189..205; Gly residues; 217..226; Polar residues; 227..240; Low complexity; 250..259; Basic and acidic residues; 260..277; Gly residues; 300..315; Gly residues; 316..330; Low complexity
Zinc Finger
514..542; C2H2-type
Region
1..70; Disordered; 121..332; Disordered
Protein Families
Elbow/Noc family
Sequence Similarities
Belongs to the Elbow/Noc family.
Clinical Relevance4
Antibody
Interaction Protein
ENSG00000136485
Interaction Count
1
Interaction Dataset
biogrid_bioplex
Supporting Publications1
| PMID | Title | Abstract |
|---|---|---|
| 38731868 | The Deep Proteomics Approach Identified Extracellular Vesicular Proteins Correlated to Extracellular Matrix in Type One and Two Endometrial Cancer. | No abstract available |