Protein detail

STALP

AMSH-like protease (AMSH-LP) (EC 3.4.19.-) (STAM-binding protein-like 1)

Protein symbol
STALP
UniProt ID
Q96FJ0
EVMP score
0.38
Frequency
1
Transmembrane count
Protein classification
EnzymesMetabolic proteinsPredicted intracellular proteins
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
AMSH-like protease (AMSH-LP) (EC 3.4.19.-) (STAM-binding protein-like 1)
Protein Class
EnzymesMetabolic proteinsPredicted intracellular proteins
Protein Function
  • Peptidases:Metallopeptidases
  • Enzymes
  • Predicted intracellular proteins
Ensembl
ENSG00000138134
Entrez Gene Symbol
STAMBPL1
Gene Synonym
ALMalphaAMSH-FPAMSH-LPbA399O19.2FLJ31524KIAA1373
Gene Description
STAM binding protein like 1
Chromosome
10
Position
88879734-88975153
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Cell SpecificNeutrophils
Function & Pathway
Protein Function
  • Peptidases:Metallopeptidases
  • Enzymes
  • Predicted intracellular proteins
Cellular Component
Molecular Function
Reactome
Mediation Categories
Other mediation
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

4 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularLOCATENoNoNoNoNo
intracellularintracellularComPPINoNoNoNoNo
intracellularintracellularGO_IntercellNoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo

Regulatory Interaction Network

0 records.

Protein Complex Composition

1 record.

Component NameComponent Gene SymbolsComponent UniProt IDStoichiometryDatabaseDatabase IDsReferences
CLTCL1PICALMSTAMBPL1P53675Q13492Q96FJ00:0:0hu.MAP2

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Polymer PrecipitationWestern blotting138731868
Sequence, Structure & Domains

Sequences

Length
436
Mass
49,783
Sequence
MDQPFTVNSLKKLAAMPDHTDVSLSPEERVRALSKLGCNITISEDITPRRYFRSGVEMERMASVYLEEGNLENAFVLYNKFITLFVEKLPNHRDYQQCAVPEKQDIMKKLKEIAFPRTDELKNDLLKKYNVEYQEYLQSKNKYKAEILKKLEHQRLIEAERKRIAQMRQQQLESEQFLFFEDQLKKQELARGQMRSQQTSGLSEQIDGSALSCFSTHQNNSLLNVFADQPNKSDATNYASHSPPVNRALTPAATLSAVQNLVVEGLRCVVLPEDLCHKFLQLAESNTVRGIETCGILCGKLTHNEFTITHVIVPKQSAGPDYCDMENVEELFNVQDQHDLLTLGWIHTHPTQTAFLSSVDLHTHCSYQLMLPEAIAIVCSPKHKDTGIFRLTNAGMLEVSACKKKGFHPHTKEPRLFSICKHVLVKDIKIIVLDLR
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q96FJ0-1; Sequence=Displayed; Name=2; IsoId=Q96FJ0-2; Sequence=VSP_014648
Alternative Sequence
420..436; CKHVLVKDIKIIVLDLR -> QKFLSGIISGTALEMEPLKIGYGPNGFPLLGISRSSSPSEQL (in isoform 2)

3D Structural Models

Turn
288..290
Helix
275..287; 328..338; 358..370; 381..383; 393..401
Beta Strand
269..272; 294..302; 305..313; 316..319; 322..325; 341..348; 350..352; 375..380; 385..391; 416..419; 421..426; 431..434
3D Structure
X-ray crystallography (3)

Domain & Motif Annotations

Motif
347..360; JAMM motif
Domain (CC)
The JAMM motif is essential for the protease activity.
Domain (FT)
269..397; MPN
Protein Families
Peptidase M67C family
Sequence Similarities
Belongs to the peptidase M67C family.
Clinical Relevance
Antibody
HPA040202
Interaction Protein
ENSG00000105982ENSG00000221867
Interaction Count
2
Interaction Dataset
intact_biogridintact_biogrid_bioplex