Protein detail

LRC46

Leucine-rich repeat-containing protein 46

Entry name
LRC46
UniProt ID
Q96FV0
EVMP confidence score
0.28
Supporting publications (n)
1
Transmembrane count
Protein classification
Predicted intracellular proteins
Basic Information
Protein Names
Leucine-rich repeat-containing protein 46
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
ENSG00000141294
Entrez Gene Symbol
LRRC46
Gene Synonym
MGC16309
Gene Description
Leucine rich repeat containing 46
Chromosome
17
Position
47831634-47837719
Supporting publications (n)
1
EVMP confidence score
0.28
Fluorescence & Localization
Tissue SpecifictestisCell SpecificEarly spermatids
Function & Pathway
Protein Function
Predicted intracellular proteins
Biological Process (3)
Mediation Categories
Other mediation
Relations & Evidence3

Ligand-Receptor Signaling (2)

2 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPI
intracellularintracellularOmniPath

Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyMass spectrometry6409858794046519537322475401894973091508438207106
Sequence, Structure & Domains

Sequences

Length
321
Mass
35,340
Sequence
MSGGKSAQGPEEGGVCITEALITKRNLTFPEDGELSEKMFHTLDELQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQVENLLDLPCLQFLDLSENLIETLKLDEFPQSLLILNLSGNSCTNQDGYRELVTEALPLLLDLDGQPVVERWISDEEDEASSDEEFPELSGPFCSERGFLKELEQELSRHREHRQQTALTEHLLRMEMQPTLTDLPLLPGVPMAGDSSPSATPAQGEETVPEAVSSPQASSPTKKPCSLIPRGHQSSFWGRKGARAATAPKASVAEAPSTTKTTAKRSKK

Domain & Motif Annotations

Repeat
45..66; LRR 1; 67..88; LRR 2; 89..110; LRR 3; 111..132; LRR 4
Coiled Coil
201..221
Domain (FT)
142..184; LRRCT
Region
235..321; Disordered
Clinical Relevance
Antibody
HPA074893
Supporting Publications1
PMIDTitleRelated sentences
22329422Quantitative proteome profiling of normal human circulating microparticles.No related sentences available