Protein detail

KLD7B

Kelch domain-containing protein 7B

Entry name
KLD7B
UniProt ID
EVMP confidence score
0.38
Supporting publications (n)
3
Transmembrane count
Protein classification
Predicted intracellular proteins
EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information11
Protein Names
Kelch domain-containing protein 7B
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Entrez Gene Symbol
Gene Synonym
MGC16635
Gene Description
Kelch domain containing 7B
Chromosome
22
Position
50545899-50551023
Supporting publications (n)
3
EVMP confidence score
0.38
Fluorescence & Localization3
Cell SpecificBreast hormone-responsive cellsSingle-Nuclei Brain Specificendothelial cellBlood Cell Specificbasophil
Function & Pathway4
Protein Function
Predicted intracellular proteins
Mediation Categories
Other mediation
Relations & Evidence3

Ligand-Receptor Signaling (2)

2 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPINoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo

Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationMass spectrometryR Sequencing24098587941307968
Sequence, Structure & Domains6

Sequences

Length
594
Mass
63,314
Sequence
MVLRSHPFPRQDRPQGSVPRAVPGSPVGPSTSTHSEDRHGPSSSVGTVIGTGTGGLVEAGGQPQPRSSETNGSPSPDPPPGLRGEGTREKSLDPLPQAAMPRGPAQPPAQRPPGPAASSSARRSQPVPQLRKRSRCEIAPSSEQEVRPAASGDPQGEAPGEGGSPAGRSGALTEKQEEARKLMVFLQRPGGWGVVEGPRKPSSRALEPATAAALRRRLDLGSCLDVLAFAQQHGEPGLAQETYALMSDNLLRVLGDPCLYRRLSAADRERILSLRTGRGRAVLGVLVLPSLYQGGRSGLPRGPRGEEPPAAAPVSLPLPAHLHVFNPRENTWRPLTQVPEEAPLRGCGLCTMHNYLFLAGGIRGSGAKAVCSNEVFCYNPLTNIWSQVRPMQQARAQLKLVALDGLLYAIGGECLYSMECYDPRTDAWTPRAPLPAGTFPVAHEAVACRGDIYVTGGHLFYRLLRYSPVKDAWDECPYSASHRRSSDIVALGGFLYRFDLLRGVGAAVMRYNTVTGSWSRAASLPLPAPAPLHCTTLGNTIYCLNPQVTATFTVSGGTAQFQAKELQPFPLGSTGVLSPFILTLPPEDRLQTSL

Domain & Motif Annotations

Compositional Bias
49..58; Gly residues; 64..74; Polar residues; 104..115; Pro residues; 116..126; Low complexity
Repeat
306..354; Kelch 1; 355..405; Kelch 2; 406..448; Kelch 3; 451..493; Kelch 4; 495..538; Kelch 5
Region
1..174; Disordered
Clinical Relevance1
Supporting Publications3
PMIDTitleAbstract
24700864Human urinary exosomes as innate immune effectors.No abstract available
32231660Natural-Killer-Derived Extracellular Vesicles: Immune Sensors and Interactors.No abstract available
38731868The Deep Proteomics Approach Identified Extracellular Vesicular Proteins Correlated to Extracellular Matrix in Type One and Two Endometrial Cancer.No abstract available