Protein detail

CP074

Uncharacterized protein C16orf74

Entry name
CP074
UniProt ID
EVMP confidence score
0.38
Supporting publications (n)
1
Transmembrane count
Protein classification
Predicted intracellular proteins
EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information11
Protein Names
Uncharacterized protein C16orf74
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Entrez Gene Symbol
Gene Synonym
MGC17624
Gene Description
Chromosome 16 open reading frame 74
Chromosome
16
Position
85690084-85751129
Supporting publications (n)
1
EVMP confidence score
0.38
Fluorescence & Localization2
Tissue SpecificretinaCell SpecificEndometrial ciliated cells
Function & Pathway4
Protein Function
Predicted intracellular proteins
Mediation Categories
Other mediation
Relations & Evidence3

Ligand-Receptor Signaling (2)

2 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPINoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo

Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential Ultracentrifugation;Ultrafiltration / Tangential Flow FiltrationMass spectrometry141063451
Sequence, Structure & Domains6

Sequences

Length
76
Mass
8,118
Sequence
MGLKMSCLKGFQMCVSSSSSSHDEAPVLNDKHLDVPDIIITPPTPTGMMLPRDLGSTVWLDETGSCPDDGEIDPEA
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; Synonyms=V1; IsoId=Q96GX8-1; Sequence=Displayed; Name=2; Synonyms=V3; IsoId=Q96GX8-2; Sequence=VSP_061477
Alternative Sequence
1..12; Missing (in isoform 2)

Domain & Motif Annotations

Region
36..41; Required for interaction with PPP3CA
Clinical Relevance1
Antibody
Supporting Publications1
PMIDTitleAbstract
30865381Surfaceome of Exosomes Secreted from the Colorectal Cancer Cell Line SW480: Peripheral and Integral Membrane Proteins Analyzed by Proteolysis and TX114.No abstract available